Evidence map›Paper›PMID 23175514›Full record

SynthesisPalliative medicine2013

Prognostic indicators of 6-month mortality in elderly people with advanced dementia: a systematic review.

Meghan A Brown, Elizabeth L Sampson, Louise Jones, Anna M Barron

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Palliative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Palliative care interventions in advanced dementia.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Palliative care interventions in advanced dementia.The Cochrane database of systematic reviews · 2016
    Pooled it
  7. Article
  8. Article
  9. Predicting hospice eligibility among dementia patients using language models.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Prognostication in Alzheimer's disease and related dementias.Journal of the American Geriatrics Society · 2025
    Article
  17. Article
  18. Article
  19. Observational
  20. Anticipatory Guidance in Dementia Across the Stages #455.Journal of palliative medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meghan A BrownDepartment of Neuroscience, College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, CA, USA.
Elizabeth L Sampson
Louise Jones
Anna M Barron

Funding

Marie Curie MCCC-FCO-11-U
6 · The paper itself

Abstract

backgroundFor end-of-life dementia patients, palliative care offers a better quality of life than continued aggressive or burdensome medical interventions. To provide the best care options to dementia sufferers, validated, reliable, sensitive, and accurate prognostic tools to identify end-of-life dementia stages are necessary.

aimTo identify accurate prognosticators of mortality in elderly advanced dementia patients consistently reported in the literature.

designSystematic literature review. DATA SOURCES: PubMed, Embase, and PsycINFO databases were searched up to September 2012. Reference lists of included studies were also searched. Inclusion criteria were studies measuring factors specifically related to 6-month outcome in patients diagnosed with dementia in any residential or health-care setting.

resultsSeven studies met the inclusion criteria, five of which were set in the United States and two in Israel. Methodology and prognostic outcomes varied greatly between the studies. All but one study found that Functional Assessment Staging phase 7c, currently widely used to assess hospice admission eligibility in the United States, was not a reliable predictor of 6-month mortality. The most common prognostic variables identified related to nutrition/nourishment, or eating habits, followed by increased risk on dementia severity scales and comorbidities.

conclusionsAlthough the majority of studies agreed that the Functional Assessment Staging 7c criterion was not a reliable predictor of 6-month mortality, we found a lack of prognosticator concordance across the literature. Further studies are essential to identify reliable, sensitive, and specific prognosticators, which can be applied to the clinical setting and allow increased availability of palliative care to dementia patients.

Indexed as

AgedDementiaGeriatric AssessmentHumansPredictive Value of TestsPrognosis

Identifiers

PMID23175514
PMCPMC3652641

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.