Evidence map›Paper›PMID 23175266›Full record

ArticleJournal of clinical microbiology2013

Detection of heterogeneity of Borrelia burgdorferi in ixodes ticks by culture-dependent and culture-independent methods.

Guang Xu, Jaime Wesker, Caitlin White, Jason Campbell, Nicholas G Reich, Stephen M Rich

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Laboratory diagnosis of Lyme disease: advances and challenges.Infectious disease clinics of North America · 2015
    Review
  5. Article
  6. Molecular Typing of Borrelia burgdorferi.Current protocols in microbiology · 2014
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guang XuLaboratory of Medical Zoology, Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA.
Jaime Wesker
Caitlin White
Jason Campbell
Nicholas G Reich
Stephen M Rich
University of Massachusetts Amherst · US

Funding

BORRELIA EVOLUTION AND POPULATION STRUCTURER01GM060759 · NIGMS · TUFTS UNIVERSITY BOSTON · PI RICH, STEPHEN M · 2000 to 2004
$1.0M
NIGMS NIH HHS R01 GM060759NIGMS NIH HHS R01-GM60759
6 · The paper itself

Abstract

Abilities to detect heterogeneity of ospC genotypes of the Lyme disease spirochete Borrelia burgdorferi in the tick vector by in vitro culture (IVC) and direct PCR (dPCR) were compared. IVC failed to detect one-third of the ospC genotypes detected by dPCR. Among IVC results, common ospC genotypes were overrepresented while occurrence of rare genotypes was underestimated.

Indexed as

Genetic VariationAnimalsAntigens, BacterialBacterial Outer Membrane ProteinsBorrelia burgdorferiFemaleGene FrequencyGenotypeIxodesMaleAntigens, BacterialBacterial Outer Membrane ProteinsOspC protein

Identifiers

PMID23175266
PMCPMC3553859
OpenAlexW2104982115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.