Evidence map›Paper›PMID 23174848›Full record

ReviewGenesis (New York, N.Y. : 2000)2013

Experimental approaches for gene regulatory network construction: the chick as a model system.

Andrea Streit, Monica Tambalo, Jingchen Chen, Timothy Grocott, Maryam Anwar, Alona Sosinsky, Claudio D Stern

Abstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. The avian embryo as a time-honoured animal model in developmental, biomedical and agricultural research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. NAR genomics and bioinformatics · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. From blastocyst to gastrula: gene regulatory networks of embryonic stem cells and early mouse embryogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea StreitDepartment of Craniofacial Development and Stem Cell Biology, King's College London, London, United Kingdom. andrea.streit@kcl.ac.uk
Monica Tambalo
Jingchen Chen
Timothy Grocott
Maryam Anwar
Alona Sosinsky
Claudio D Stern

Funding

Gene Regulation of Cranial Sensory Placode DevelopmentR01DE022065 · NIDCR · GEORGE WASHINGTON UNIVERSITY · PI MOODY, SALLY ANN · 2011 to 2015
$1.7M
Biotechnology and Biological Sciences Research Council BB/G000972/1Medical Research Council MR/K001744/1NIDCR NIH HHS R01 DE022065
6 · The paper itself

Abstract

Setting up the body plan during embryonic development requires the coordinated action of many signals and transcriptional regulators in a precise temporal sequence and spatial pattern. The last decades have seen an explosion of information describing the molecular control of many developmental processes. The next challenge is to integrate this information into logic "wiring diagrams" that visualize gene actions and outputs, have predictive power and point to key control nodes. Here, we provide an experimental workflow on how to construct gene regulatory networks using the chick as model system.

Indexed as

Gene Regulatory NetworksAnimalsChick EmbryoChickensEnhancer Elements, GeneticGene Expression ProfilingGene Expression Regulation

Identifiers

PMID23174848
PMCPMC3626748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.