Evidence map›Paper›PMID 23174296›Full record

ArticleCurrent biology : CB2012

Histones: sequestered by Jabba in fatty storehouse.

William F Marzluff, Deirdre C Tatomer

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

William F MarzluffDepartment of Biochemistry, University of North Carolina at Chapel Hill School of Medicine, 208 Fordham Hall, Campus Box # 7100, Chapel Hill, NC 27599, USA. marzluff@med.unc.edu
Deirdre C Tatomer
University of North Carolina at Chapel Hill · US

Funding

HISTONE MRNA REGULATION IN DEVELOPMENTR01GM058921 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DURONIO, ROBERT J, MARZLUFF, WILLIAM F. · 1999 to 2025
$11.6M
CONTROL OF HISTONE MRNA SYNTHESISR01GM029832 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DOMINSKI, ZBIGNIEW, MARZLUFF, WILLIAM F. · 1985 to 2022
$9.0M
NIGMS NIH HHS R01 GM029832NIGMS NIH HHS R01 GM058921
6 · The paper itself

Abstract

A paper in this issue shows that histones H2a and H2b are stored in lipid droplets in Drosophila embryos complexed with the protein Jabba. In Jabba mutant embryos, histones H2a and H2b are degraded but embryos survive by translating stored histone mRNA.

Indexed as

AnimalsCarrier ProteinsDrosophilaDrosophila ProteinsGene Expression Regulation, DevelopmentalHistonesMutationRNA, MessengerCarrier ProteinsDrosophila ProteinsHistonesjabba protein, DrosophilaRNA, Messenger

Identifiers

PMID23174296
PMCPMC3711088
OpenAlexW2001963591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.