Evidence map›Paper›PMID 23173755›Full record

Trial reportBMC surgery2012

Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly.

Rita Compagna, Gabriele Vigliotti, Guido Coretti, Maurizio Amato, Giovanni Aprea, Alessandro Puzziello, Carmelo Militello, Fabrizio Iacono, Domenico Prezioso, Bruno Amato

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Mode of anesthesia, mortality and outcome in geriatric patients.Zeitschrift fur Gerontologie und Geriatrie · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rita CompagnaDepartment of General, Geriatric, Oncologic Surgery and advanced technologies, University Federico II of Naples, Via Pansini 5, 80131 Naples, Italy. ritacompagna@libero.it
Gabriele Vigliotti
Guido Coretti
Maurizio Amato
Giovanni Aprea
Alessandro Puzziello
Carmelo Militello
Fabrizio Iacono
Domenico Prezioso
Bruno Amato
University of Naples Federico II · ITFederico II University Hospital · ITMagna Graecia University · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe inguinal hernia is one of the most common diseases in the elderly. Treatment of this type of pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there has been growing emphasis on the role of local anesthesia.

methodsThe aim of our study was to compare intra-and postoperative analgesia obtained by the use of levobupivacaine compared with that of bupivacaine. Bupivacaine is one of the main local anesthetics used in the intervention of inguinal hernioplasty. Levobupivacaine is an enantiomer of racemic bupivacaine with less cardiotoxicity and neurotoxicity. The study was conducted from April 2010 to May 2012. We collected data of forty male patients, aged between 73 and 85 years, who underwent inguinal hernioplasty with local anesthesia for the first time.

resultsMinimal pain is the same in both groups. Mild pain was more frequent in the group who used bupivacaine, moderate pain was slightly more frequent in the group who used levobupivacaine, and the same for intense pain. It is therefore evident how Bupivacaine is slightly less preferred after four and twenty four hours, while the two drugs seem to have the same effect at a distance of twelve and forty-eight hours. Bupivacaine shows a significantly higher number of complications, as already demonstrated by previous studies. The request for an analgesic was slightly higher in patients receiving levobupivacaine.

conclusionsAfter considering all these elements, we can conclude that the clinical efficacy of levobupivacaine and racemic bupivacaine are essentially similar, when used under local intervention of inguinal hernioplasty.

Indexed as

Anesthesia, LocalAnesthetics, LocalBupivacaineAgedAged, 80 and overAnalgesicsAnalysis of VarianceChi-Square DistributionDouble-Blind MethodHernia, InguinalHerniorrhaphyHumansIntraoperative PeriodLevobupivacaineMalePain MeasurementAnalgesicsAnesthetics, LocalBupivacaineLevobupivacaine

Identifiers

PMID23173755
PMCPMC3499198
OpenAlexW2033952590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.