ArticleProceedings. Biological sciences2013
The effect of sexual harassment on lethal mutation rate in female Drosophila melanogaster.
Article in Proceedings. Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Coevolution of longevity and female germline maintenance.Proceedings. Biological sciences · 2024Article
- Increased male investment in sperm competition results in reduced maintenance of gametes.PLoS biology · 2023Article
- Kin but less than kind: within-group male relatedness does not increase female fitness in seed beetles.Proceedings. Biological sciences · 2019Article
- Behavioural elements and sensory cues involved in sexual isolation betweenRoyal Society open science · 2018Article
- Temperature effects on life-history trade-offs, germline maintenance and mutation rate under simulated climate warming.Proceedings. Biological sciences · 2017Article
- Polyandry enhances offspring viability with survival costs to mothers only when mating exclusively with virgin males inEcology and evolution · 2017Article
- Are flies kind to kin? The role of intra- and inter-sexual relatedness in mediating reproductive conflict.Proceedings. Biological sciences · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rate by which new mutations are introduced into a population may have far-reaching implications for processes at the population level. Theory assumes that all individuals within a population have the same mutation rate, but this assumption may not be true. Compared with individuals in high condition, those in poor condition may have fewer resources available to invest in DNA repair, resulting in elevated mutation rates. Alternatively, environmentally induced stress can result in increased investment in DNA repair at the expense of reproduction. Here, we directly test whether sexual harassment by males, known to reduce female condition, affects female capacity to alleviate DNA damage in Drosophila melanogaster fruitflies. Female gametes can repair double-strand DNA breaks in sperm, which allows manipulating mutation rate independently from female condition. We show that male harassment strongly not only reduces female fecundity, but also reduces the yield of dominant lethal mutations, supporting the hypothesis that stressed organisms invest relatively more in repair mechanisms. We discuss our results in the light of previous research and suggest that social effects such as density and courtship can play an important and underappreciated role in mediating condition-dependent mutation rate.
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Registered trials
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