Evidence map›Paper›PMID 23172972›Full record

Trial reportDiabetes care2013

Resistance versus aerobic exercise: acute effects on glycemia in type 1 diabetes.

Jane E Yardley, Glen P Kenny, Bruce A Perkins, Michael C Riddell, Nadia Balaa, Janine Malcolm, Pierre Boulay, Farah Khandwala, Ronald J Sigal

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05736263 (Setting a New Algorithm For the Management of Exercise-induced Glycemic Variations in Patients With Type 1 Diabetes in Intensive Therapy With Hybrid Closed-loop Systems), which is not on this map. Cited by 109 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05736263 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Setting a New Algorithm For the Management of Exercise-induced Glycemic Variations in Patients With Type 1 Diabetes in Intensive Therapy With Hybrid Closed-loop Systems

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2023 to 2024Enrolled50ConditionsType 1 Diabetes, ExerciseArmsModerate intensity exercise, High intensity interval exercise, Combined exercise, Resistance exercise
3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 1 synthesis or guideline pooled it, 243 citations in OpenAlex.

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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Jane E YardleyHuman and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Ontario, Canada.
Glen P Kenny
Bruce A Perkins
Michael C Riddell
Nadia Balaa
Janine Malcolm
Pierre Boulay
Farah Khandwala
Ronald J Sigal
Institute of Population and Public Health · CAUniversity of Ottawa · CAAlberta Health Services · CAChamplain Regional College · CAUniversity Health Network · CAUniversity of Calgary · CAYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn type 1 diabetes, small studies have found that resistance exercise (weight lifting) reduces HbA(1c). In the current study, we examined the acute impacts of resistance exercise on glycemia during exercise and in the subsequent 24 h compared with aerobic exercise and no exercise. RESEARCH DESIGN AND

methodsTwelve physically active individuals with type 1 diabetes (HbA(1c) 7.1 ± 1.0%) performed 45 min of resistance exercise (three sets of seven exercises at eight repetitions maximum), 45 min of aerobic exercise (running at 60% of Vo(2max)), or no exercise on separate days. Plasma glucose was measured during and for 60 min after exercise. Interstitial glucose was measured by continuous glucose monitoring 24 h before, during, and 24 h after exercise.

resultsTreatment-by-time interactions (P < 0.001) were found for changes in plasma glucose during and after exercise. Plasma glucose decreased from 8.4 ± 2.7 to 6.8 ± 2.3 mmol/L (P = 0.008) during resistance exercise and from 9.2 ± 3.4 to 5.8 ± 2.0 mmol/L (P = 0.001) during aerobic exercise. No significant changes were seen during the no-exercise control session. During recovery, glucose levels did not change significantly after resistance exercise but increased by 2.2 ± 0.6 mmol/L (P = 0.023) after aerobic exercise. Mean interstitial glucose from 4.5 to 6.0 h postexercise was significantly lower after resistance exercise versus aerobic exercise.

conclusionsResistance exercise causes less initial decline in blood glucose during the activity but is associated with more prolonged reductions in postexercise glycemia than aerobic exercise. This might account for HbA(1c) reductions found in studies of resistance exercise but not aerobic exercise in type 1 diabetes.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 1ExerciseFemaleGlycated HemoglobinHumansMaleBlood GlucoseGlycated Hemoglobin

Identifiers

PMID23172972
PMCPMC3579339
OpenAlexW2050580643

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.