ArticleNature2012
Water structural transformation at molecular hydrophobic interfaces.
Article in Nature, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.
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Who cites it
111 citing papers in PubMed.
- Water Structure within Ternary Solvents Suggests Nanophase Formation.Journal of the American Chemical Society · 2026Article
- Achieving Robust and High-Transmittance Bioceramics with Minimal Organic Additives via a Supervariate Strategy.ACS nano · 2026Article
- Structure of Water in the First Hydration Shell of the Highly Hydrophobic Anthracene.The journal of physical chemistry. A · 2026Article
- Spiers Memorial Lecture: Vibrations at interfaces.Faraday discussions · 2026Article
- Structural Response of the Water Dimer to an Electric Field.ACS omega · 2026Article
- Langmuir-Hinshelwood pathway enables 1000-h stable nitrate-to-ammonia electroreduction at 1 A cmNature communications · 2026Article
- The role of hydration in the removal of glyphosate (GLY) and aminomethylphosphonic acid (AMPA) by nanofiltration membranes.Nature communications · 2026Article
- Piezoelectric activation of dual lattice-oxygen mechanism through OHNature communications · 2026Article
- Single-engineered-residue solvation perturbations regulate global protein architecture and function.Nature communications · 2026Article
- Dynamics of Solvating Water As a Probe of Polymers and Supramolecular Structures.Chemical reviews · 2026Review
- Concurrent Formation of Ice Network within Mineral Colloids with Suppressed Volume Expansion.The journal of physical chemistry letters · 2026Article
- Electric fields at hydrophobic water interfaces: spectroscopic evidence, physical origin, and implications on reactivity.Chemical Society reviews · 2026Review
- Influence of plasticizer type on the structure and drug release characteristics of LM-pectin hydrogels.Turkish journal of chemistry · 2026Article
- Probing Residual Water in G-Quadruplex Structures through Molecular Vibrations.The journal of physical chemistry. B · 2025Article
- Dynamic Sub-Nanoscale "Water Fingers" in Interfacial Polymerization.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Terahertz calorimetry spotlights the role of water in biological processes.Nature reviews. Chemistry · 2025Review
- DNA-Binding Properties of Non-Intercalating Water-Soluble Organometallic Ir(III) Luminophores.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Photon-counting Raman spectroscopy at a MHz spectral rate for biochemical imaging of an entire organism.Nature communications · 2025Article
- Extension of the molar absorption coefficient for non-ideal mixtures: an application to aqueous monovalent alcohol solutions.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- Article
51 more citing papers are in PubMed but not listed here.
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Hydrophobic hydration is considered to have a key role in biological processes ranging from membrane formation to protein folding and ligand binding. Historically, hydrophobic hydration shells were thought to resemble solid clathrate hydrates, with solutes surrounded by polyhedral cages composed of tetrahedrally hydrogen-bonded water molecules. But more recent experimental and theoretical studies have challenged this view and emphasized the importance of the length scales involved. Here we report combined polarized, isotopic and temperature-dependent Raman scattering measurements with multivariate curve resolution (Raman-MCR) that explore hydrophobic hydration by mapping the vibrational spectroscopic features arising from the hydrophobic hydration shells of linear alcohols ranging from methanol to heptanol. Our data, covering the entire 0-100 °C temperature range, show clear evidence that at low temperatures the hydration shells have a hydrophobically enhanced water structure with greater tetrahedral order and fewer weak hydrogen bonds than the surrounding bulk water. This structure disappears with increasing temperature and is then, for hydrophobic chains longer than ~1 nm, replaced by a more disordered structure with weaker hydrogen bonds than bulk water. These observations support our current understanding of hydrophobic hydration, including the thermally induced water structural transformation that is suggestive of the hydrophobic crossover predicted to occur at lengths of ~1 nm (refs 5, 9, 10, 14).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.