ArticleAmerican journal of epidemiology2012
Allergy and risk of childhood acute lymphoblastic leukemia: a population-based and record-based study.
Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Allergies and Childhood Acute Lymphoblastic Leukemia: A Case-Control Study and Meta-analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Pooled it
- Review
- Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.BMC medicine · 2024Article
- Acute lymphoid leukemia etiopathogenesis.Molecular biology reports · 2021Review
- Agents in Development for Childhood Acute Lymphoblastic Leukemia.Paediatric drugs · 2018Review
- Atopy and Specific Cancer Sites: a Review of Epidemiological Studies.Clinical reviews in allergy & immunology · 2016Review
- Association of atopic diseases and parvovirus B19 with acute lymphoblastic leukemia in childhood and adolescence in the northeast of Brazil.International journal of clinical oncology · 2016Article
- Reported associations between asthma and acute lymphoblastic leukemia: insights from a hybrid simulation study.European journal of epidemiology · 2016Article
- Association of asthma with the risk of acute leukemia and non-Hodgkin lymphoma.Molecular and clinical oncology · 2015Article
- Immune-related conditions and acute leukemia in children with Down syndrome: a Children's Oncology Group report.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015Article
- Allergic diseases and risk of hematopoietic malignancies in a cohort of postmenopausal women: a report from the Iowa Women's Health Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014Article
- Associations between allergies and risk of hematologic malignancies: results from the VITamins and lifestyle cohort study.American journal of hematology · 2013Article
- Article
- Allergy and acute leukaemia in children with Down syndrome: a population study. Report from the Mexican inter-institutional group for the identification of the causes of childhood leukaemia.British journal of cancer · 2013Article
- Invited commentary: childhood acute lymphoblastic leukemia and allergies: biology or bias?American journal of epidemiology · 2012Article
- Perspectives on the causes of childhood leukemia.Chemico-biological interactions · 2012Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A deficit of normal immune stimulation in early childhood is a suspected risk factor for both childhood acute lymphoblastic leukemia (ALL) and allergies. The present study utilized a population-based case-control design using medical claims data from the National Health Insurance Research Database of Taiwan to evaluate the association between allergy and childhood leukemia. Eight hundred forty-six childhood ALL patients who were newly diagnosed during 2000 to 2008 and were older than 1 but less than 10 years of age were individually matched with 3,374 controls based on sex, birth date, and time of diagnosis (reference date for the controls). Conditional logistic regression was performed to assess the association between childhood ALL and allergies. An increased risk of ALL was observed with having an allergy less than 1 year before the case's ALL diagnosis (odds ratio (OR) = 1.7, 95% confidence interval (CI): 1.5, 2.0), more than 1 year before the case's diagnosis (OR = 1.3, 95% CI: 1.1, 1.5), and before the age of 1 year (OR = 1.4, 95% CI: 1.1, 1.7). These results suggest that the pathogenesis of childhood ALL and allergy share a common biologic mechanism.
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