Evidence map›Paper›PMID 23171629›Full record

ArticleBMC biology2012

Logic modeling and the ridiculome under the rug.

Michael L Blinov, Ion I Moraru

Abstract read
In one paragraph

Article in BMC biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael L BlinovCenter for Cell Analysis and Modeling, University of Connecticut Health Center, Cell and Genome Sciences Building, 400 Farmington Ave, Farmington, CT 06030-6406, USA.
Ion I Moraru

Funding

VIRTUAL FCSP41RR013186 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LOEW, LESLIE M · 1998 to 2011
$14.2M
Bringing BioNetGen Rule-Based Modeling to Virtual Cell UsersR01GM095485 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI BLINOV, MICHAEL, MORARU, ION I. · 2011 to 2013
$867k
NCRR NIH HHS RR013186NIGMS NIH HHS GM095485
6 · The paper itself

Abstract

Logic-derived modeling has been used to map biological networks and to study arbitrary functional interactions, and fine-grained kinetic modeling can accurately predict the detailed behavior of well-characterized molecular systems; at present, however, neither approach comes close to unraveling the full complexity of a cell. The current data revolution offers significant promises and challenges to both approaches - and could bring them together as it has spurred the development of new methods and tools that may help to bridge the many gaps between data, models, and mechanistic understanding.

Indexed as

Metabolic Networks and PathwaysModels, BiologicalSystems AnalysisComputer SimulationSoftwareSystems Biology

Identifiers

PMID23171629
PMCPMC3503555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.