ArticleBMC genomics2012
Genome sequence of the necrotrophic fungus Penicillium digitatum, the main postharvest pathogen of citrus.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
94 citing papers in PubMed, 245 citations in OpenAlex.
- Green Mold of Citrus: Recent Insights intoJournal of agricultural and food chemistry · 2026Review
- An Overview of MajorJournal of fungi (Basel, Switzerland) · 2026Review
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- Biochemical, Structural, and Conformational Characterization of a Fungal Ethylene-Forming Enzyme.Biochemistry · 2025Article
- A conserved fungal effector disturbs CaNature communications · 2025Article
- Comparative genome analysis of patulin-producingPeerJ · 2025Article
- Increasing the efficiency of CRISPR/Cas9-mediated genome editing in the citrus postharvest pathogen Penicillium digitatum.Fungal biology and biotechnology · 2024Article
- Transcriptome Analysis ofMicroorganisms · 2024Article
- Inhibitory Properties of Cinnamon Bark Oil against Postharvest PathogenJournal of fungi (Basel, Switzerland) · 2024Article
- Discovery and Transcriptional Profiling ofJournal of fungi (Basel, Switzerland) · 2024Article
- Morphological and transcriptional analysis of Colletotrichum lindemuthianum race 7 during early stages of infection in common bean.Genetics and molecular biology · 2024Article
- Comparative transcriptome analysis to unveil genes affecting the host cuticle destruction in Metarhizium rileyi.Current genetics · 2023Article
- Multifunctional regulation of NADPH oxidase in growth, microsclerotia formation and virulence in Metarhizium rileyi.Biotechnology letters · 2023Article
- Transcriptomic Profile of Penicillium digitatum Reveals Novel Aspects of the Mode of Action of the Antifungal Protein AfpB.Microbiology spectrum · 2023Article
- Efficient control of the fungal pathogensHeliyon · 2023Article
- FungalBraid 2.0: expanding the synthetic biology toolbox for the biotechnological exploitation of filamentous fungi.Frontiers in bioengineering and biotechnology · 2023Article
- The Role of ABA in the Interaction between Citrus Fruit andInternational journal of molecular sciences · 2022Article
- Unveiling the complete genome sequence of Alicyclobacillus acidoterrestris DSM 3922T, a taint-producing strain.G3 (Bethesda, Md.) · 2022Article
- The plasma membrane HApplied microbiology and biotechnology · 2022Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPenicillium digitatum is a fungal necrotroph causing a common citrus postharvest disease known as green mold. In order to gain insight into the genetic bases of its virulence mechanisms and its high degree of host-specificity, the genomes of two P. digitatum strains that differ in their antifungal resistance traits have been sequenced and compared with those of 28 other Pezizomycotina.
resultsThe two sequenced genomes are highly similar, but important differences between them include the presence of a unique gene cluster in the resistant strain, and mutations previously shown to confer fungicide resistance. The two strains, which were isolated in Spain, and another isolated in China have identical mitochondrial genome sequences suggesting a recent worldwide expansion of the species. Comparison with the closely-related but non-phytopathogenic P. chrysogenum reveals a much smaller gene content in P. digitatum, consistent with a more specialized lifestyle. We show that large regions of the P. chrysogenum genome, including entire supercontigs, are absent from P. digitatum, and that this is the result of large gene family expansions rather than acquisition through horizontal gene transfer. Our analysis of the P. digitatum genome is indicative of heterothallic sexual reproduction and reveals the molecular basis for the inability of this species to assimilate nitrate or produce the metabolites patulin and penicillin. Finally, we identify the predicted secretome, which provides a first approximation to the protein repertoire used during invasive growth.
conclusionsThe complete genome of P. digitatum, the first of a phytopathogenic Penicillium species, is a valuable tool for understanding the virulence mechanisms and host-specificity of this economically important pest.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.