Evidence map›Paper›PMID 23171151›Full record

ArticleNeurocase2014

Neuropsychological, behavioral, and anatomical evolution in right temporal variant frontotemporal dementia: a longitudinal and post-mortem single case analysis.

Maya L Henry, Stephen M Wilson, Jennifer M Ogar, Manu S Sidhu, Katherine P Rankin, Tatiana Cattaruzza, Bruce L Miller, Maria Luisa Gorno-Tempini, William W Seeley

Open access · greenAbstract readCase Reports
In one paragraph

Article in Neurocase, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
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  3. Observational
  4. Article
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  7. Review
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  11. Review
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  13. Article
  14. Review
  15. Visuospatial Functioning in the Primary Progressive Aphasias.Journal of the International Neuropsychological Society : JINS · 2018
    Article
  16. Review
  17. Geschwind Syndrome in frontotemporal lobar degeneration: Neuroanatomical and neuropsychological features over 9 years.Cortex; a journal devoted to the study of the nervous system and behavior · 2017
    Article
  18. A Clinical Guide to Frontotemporal Dementias.Focus (American Psychiatric Publishing) · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Maya L Henrya Memory and Aging Center, Department of Neurology , University of California San Francisco , San Francisco , CA , USA.
Stephen M Wilson
Jennifer M Ogar
Manu S Sidhu
Katherine P Rankin
Tatiana Cattaruzza
Bruce L Miller
Maria Luisa Gorno-Tempini
William W Seeley
University Memory and Aging Center · USOspedale di Cattinara · ITSan Francisco State University · USUniversity of Arizona · USUniversity of California, San Francisco · US

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Transgenic Mouse Models of Tau PathologiesP01AG017586 · NIA · UNIVERSITY OF PENNSYLVANIA · PI LEE, VIRGINIA M · 2000 to 2021
$37.3M
PrPSc SPECIFIC INTERACTION WITH NOVEL PrP-Fc FUSION PROTEINSP50AG023501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MILLER, BRUCE L · 2004 to 2018
$27.1M
Progressive Aphasia Cognition Anatomy and ProgressionR01NS050915 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARIA LUISA GORNO TEMPINI · 2004 to 2026
$11.0M
Attention and Semantic Evaluation as Predictors of Empathy in Healthy Aging and Frontotemporal DementiaRF1AG029577 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RANKIN, KATHERINE P · 2019 to 2019
$4.0M
Measuring Altered Social Behavior in Neurodegenerative DiseaseR01AG029577 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RANKIN, KATHERINE P · 2008 to 2018
$3.6M
Selective Vulnerability in Frontotemporal DementiaR01AG033017 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEELEY, WILLIAM W · 2009 to 2013
$2.5M
Primary Progressive Aphasia: Neural Bases and RehabilitationF32DC010945 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HENRY, MAYA · 2010 to 2012
$124k
NIA NIH HHS P01 AG017586NIA NIH HHS P01 AG019724NIA NIH HHS P50 AG023501NIA NIH HHS R01 AG033017NIA NIH HHS RF1 AG029577NIDCD NIH HHS F32 DC010945NIDCD NIH HHS F32DC010945NINDS NIH HHS R01 NS050915
6 · The paper itself

Abstract

We describe a patient with semantic variant of frontotemporal dementia who received longitudinal clinical evaluations and structural MRI scans and subsequently came to autopsy. She presented with early behavior changes and semantic loss for foods and people and ultimately developed a pervasive semantic impairment affecting social-emotional as well as linguistic domains. Imaging revealed predominant atrophy of the right temporal lobe, with later involvement of the left, and pathology confirmed bilateral temporal involvement. Findings support the view that left and right anterior temporal lobes serve as semantic hubs that may be affected differentially in semantic variant by early, relatively unilateral damage.

Indexed as

AgedFemaleFrontotemporal DementiaHumansLongitudinal StudiesNeuropsychological TestsTemporal Lobe

Identifiers

PMID23171151
PMCPMC3775867
OpenAlexW2037435480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.