ArticleBMC evolutionary biology2012
Rather than by direct acquisition via lateral gene transfer, GHF5 cellulases were passed on from early Pratylenchidae to root-knot and cyst nematodes.
Article in BMC evolutionary biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 37 citations in OpenAlex.
- Integrative taxonomy and mitogenome characterization of the root-knot nematode Meloidogyne silvestris.Scientific reports · 2026Article
- Master of Puppets: How Microbiota Drive the Nematoda Ecology and Evolution?Ecology and evolution · 2025Review
- Recombinase Polymerase Amplification assay for detection of the British root-knot nematode,Journal of nematology · 2024Article
- In silico secretome analyses of the polyphagous root-knot nematode Meloidogyne javanica: a resource for studying M. javanica secreted proteins.BMC genomics · 2023Article
- Application Potential of Bacterial Volatile Organic Compounds in the Control of Root-Knot Nematodes.Molecules (Basel, Switzerland) · 2022Review
- Molecular Characterization of Three B-1,4-Endoglucanase Genes inPlants (Basel, Switzerland) · 2021Article
- Current Insights into Migratory Endoparasitism: Deciphering the Biology, Parasitism Mechanisms, and Management Strategies of Key Migratory Endoparasitic Phytonematodes.Plants (Basel, Switzerland) · 2020Review
- Phylogenetic studies on threeJournal of nematology · 2019Article
- Functional Variation of Two Novel Cellulases,International journal of molecular sciences · 2018Article
- Glycoside Hydrolase (GH) 45 and 5 Candidate Cellulases in Aphelenchoides besseyi Isolated from Bird's-Nest Fern.PloS one · 2016Article
- The evolution of parasitism in Nematoda.Parasitology · 2015Review
- Article
- Analysis of the transcriptome of Hirschmanniella oryzae to explore potential survival strategies and host-nematode interactions.Molecular plant pathology · 2014Article
- Distribution and evolution of glycoside hydrolase family 45 cellulases in nematodes and fungi.BMC evolutionary biology · 2014Article
- Top 10 plant-parasitic nematodes in molecular plant pathology.Molecular plant pathology · 2013Review
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8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant parasitic nematodes are unusual Metazoans as they are equipped with genes that allow for symbiont-independent degradation of plant cell walls. Among the cell wall-degrading enzymes, glycoside hydrolase family 5 (GHF5) cellulases are relatively well characterized, especially for high impact parasites such as root-knot and cyst nematodes. Interestingly, ancestors of extant nematodes most likely acquired these GHF5 cellulases from a prokaryote donor by one or multiple lateral gene transfer events. To obtain insight into the origin of GHF5 cellulases among evolutionary advanced members of the order Tylenchida, cellulase biodiversity data from less distal family members were collected and analyzed.
resultsSingle nematodes were used to obtain (partial) genomic sequences of cellulases from representatives of the genera Meloidogyne, Pratylenchus, Hirschmanniella and Globodera. Combined Bayesian analysis of ≈ 100 cellulase sequences revealed three types of catalytic domains (A, B, and C). Represented by 84 sequences, type B is numerically dominant, and the overall topology of the catalytic domain type shows remarkable resemblance with trees based on neutral (= pathogenicity-unrelated) small subunit ribosomal DNA sequences. Bayesian analysis further suggested a sister relationship between the lesion nematode Pratylenchus thornei and all type B cellulases from root-knot nematodes. Yet, the relationship between the three catalytic domain types remained unclear. Superposition of intron data onto the cellulase tree suggests that types B and C are related, and together distinct from type A that is characterized by two unique introns.
conclusionsAll Tylenchida members investigated here harbored one or multiple GHF5 cellulases. Three types of catalytic domains are distinguished, and the presence of at least two types is relatively common among plant parasitic Tylenchida. Analysis of coding sequences of cellulases suggests that root-knot and cyst nematodes did not acquire this gene directly by lateral genes transfer. More likely, these genes were passed on by ancestors of a family nowadays known as the Pratylenchidae.
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