Evidence map›Paper›PMID 23170870›Full record

ArticleMycoses2013

Candiduria in haematologic malignancy patients without a urinary catheter: nothing more than a frailty marker?

Sarah P Georgiadou, Jeffrey Tarrand, Nikolaos V Sipsas, Dimitrios P Kontoyiannis

Open access · greenAbstract read
In one paragraph

Article in Mycoses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Guideline
  2. A 3-year study ofFrontiers in cellular and infection microbiology · 2023
    Article
  3. Candida urinary tract infections in adults.World journal of urology · 2020
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sarah P GeorgiadouDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Jeffrey Tarrand
Nikolaos V Sipsas
Dimitrios P Kontoyiannis
The University of Texas MD Anderson Cancer Center · USNational and Kapodistrian University of Athens · GR

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Manipulation of Host Angiogenesis as a Therapeutic Strategy against Invasive PulmR03AI083733 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONTOYIANNIS, DIMITRIOS P · 2009 to 2010
$154k
NCI NIH HHS CA016672NCI NIH HHS P30 CA016672NIAID NIH HHS R03 AI083733
6 · The paper itself

Abstract

There is scarcity of data regarding significance of candiduria in patients with haematologic malignancies and its association with invasive candidiasis. To that end, we retrospectively evaluated all hospitalised, non-intensive care unit patients with haematologic malignancies and candiduria during a 10-year period (2001-2011). To decrease the possibility of bladder colonisation and sample contamination, we excluded all patients with candiduria who had urinary catheters and those with concomitant bacteriuria. Twenty-four such patients (21 females) were identified, with median age at diagnosis 62 years (range, 20-82 years). Acute leukaemia was the most common underlying disease (54%); 62% of these cases were not in remission. Twenty-nine percent of the patients had diabetes mellitus and 25% were neutropenic. The most common isolated Candida species was Candida glabrata (37%), followed by C. albicans (29%). Only 8% of them had urinary tract infection symptoms. However, 88% received systemic antifungals. Candidemia and crude mortality rates at 4 weeks were low (4% and 12% respectively). Isolated candiduria in patients with haematologic malignancies has risk factors similar to those in other hospitalised patients, and it does not seem to be a strong predictor of subsequent invasive candidiasis.

Indexed as

Urinary CathetersAdultAgedAged, 80 and overAntifungal AgentsCandida glabrataCandidiasis, InvasiveDiabetes MellitusFemaleHematologic NeoplasmsHumansLeukemia, Myeloid, AcuteMiddle AgedNeutropeniaPyuriaRetrospective StudiesAntifungal Agents

Identifiers

PMID23170870
PMCPMC3883107
OpenAlexW1834009066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.