Evidence map›Paper›PMID 23170828›Full record

Trial reportInfluenza and other respiratory viruses2013

Advantage of meditation over exercise in reducing cold and flu illness is related to improved function and quality of life.

Chidi N Obasi, Roger Brown, Tola Ewers, Shari Barlow, Michele Gassman, Aleksandra Zgierska, Christopher L Coe, Bruce Barrett

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Influenza and other respiratory viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01057771 (Meditation and Exercise for Prevention of Acute Respiratory Infection), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01057771 phase2 / phase3completednot on this map

Meditation and Exercise for Prevention of Acute Respiratory Infection

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2009 to 2010Enrolled154ConditionsAcute Respiratory InfectionArmsMeditation, Exercise
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Article
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  9. Yoga, immunity and COVID-19: A scoping review.Journal of family medicine and primary care · 2022
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  19. Self-Reported Mental Health Predicts Acute Respiratory Infection.WMJ : official publication of the State Medical Society of Wisconsin · 2015
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  20. Item reduction of the Wisconsin Upper Respiratory Symptom Survey (WURSS-21) leads to the WURSS-11.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chidi N ObasiDepartment of Family Medicine, University of Wisconsin-Madison.Schools of Nursing, Medicine and Public Health - Research Design & Statistics Unit, University of Wisconsin-Madison.Harlow Center for Biological Psychology, University of Wisconsin-Madison, Madison, WI, USA.
Roger Brown
Tola Ewers
Shari Barlow
Michele Gassman
Aleksandra Zgierska
Christopher L Coe
Bruce Barrett

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Meditation and Exercise for Prevention of Acute Respiratory InfectionR01AT004313 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2009 to 2010
$1.2M
Mindfulness Meditation for Alcohol Relapse PreventionK23AA017508 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI ZGIERSKA, ALEKSANDRA EWA · 2009 to 2013
$918k
Mentoring and research in patient-oriented medicineK24AT006543 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2012 to 2016
$818k
NCATS NIH HHS UL1 TR000427NCCIH NIH HHS 1R01AT004313NCCIH NIH HHS K24 AT006543NCCIH NIH HHS R01 AT004313NCRR NIH HHS 1UL1RR025011NCRR NIH HHS UL1 RR025011NIAAA NIH HHS K23 AA017508PHS HHS T32HP10010
6 · The paper itself

Abstract

purposeTo examine whether apparent advantages following training in meditation over exercise can be attributed to specific symptoms, functional impairments, or quality-of-life indicators assessed by the Wisconsin Upper Respiratory Symptom Survey (WURSS-24).

methodsResults from the randomized controlled trial "Meditation or Exercise for Preventing Acute Respiratory Illness" showed mean global severity and total days of illness were worse in control (358, 8·9) compared with exercise (248, 5·1) or meditation (144, 5·0). Global severity of illness was estimated using area under the curve from daily self-reported severity scores on the WURSS-24. For this project, we estimated within-group WURSS item-level severity and between-group effect sizes (Cohen's "d" statistic) relative to control. The item-level effect sizes were grouped into (i) symptom and (ii) function and quality of life domains.

resultsAmong the three groups, mediators showed the lowest severity estimates for 21 of 22 WURSS items. Item-level Cohen's "d" indicated most benefit was evident in WURSS items representing function and quality of life. Compared with exercise, meditation fostered larger reductions in illness severity, although due mostly to improved function and the quality of life domain (d=-0·33, P<0·001) compared with symptom domain (d=-0·22, P<0·001).

conclusionsThe apparent advantage of training in meditation over exercise for reducing cold and flu illness is explained more by improved function and quality of life than by a reduction in symptom severity.

Indexed as

ExerciseMeditationAgedCommon ColdFemaleHumansInfluenza, HumanMaleMiddle AgedQuality of LifeSeverity of Illness IndexAcute respiratory infectionexercisefunction and quality of lifemeditation

Identifiers

PMID23170828
PMCPMC3582749

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.