ArticleMarine drugs2012
Structural analysis of a heteropolysaccharide from Saccharina japonica by electrospray mass spectrometry in tandem with collision-induced dissociation tandem mass spectrometry (ESI-CID-MS/MS).
Article in Marine drugs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- The effect of Gougunao tea polysaccharide on lipid metabolism in hyperlipidemia induced by a high-fat diet and its structural characteristics.Current research in food science · 2025Article
- Optimization of the Preparation Process of Glucuronomannan Oligosaccharides and Their Effects on the Gut Microbiota in MPTP-Induced PD Model Mice.Marine drugs · 2024Article
- Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant.Glycoconjugate journal · 2024Article
- Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin.Viruses · 2024Article
- Anti-SARS-CoV-2 Activity of Polysaccharides Extracted fromMarine drugs · 2023Article
- Interactions of marine sulfated glycans with antithrombin and platelet factor 4.Frontiers in molecular biosciences · 2022Article
- Sulfatases: Critical Enzymes for Algal Polysaccharide Processing.Frontiers in plant science · 2022Review
- The structure-activity relationship of the interactions of SARS-CoV-2 spike glycoproteins with glucuronomannan and sulfated galactofucan from Saccharina japonica.International journal of biological macromolecules · 2020Article
- Interactions of fibroblast growth factors with sulfated galactofucan from Saccharina japonica.International journal of biological macromolecules · 2020Article
- Structural characteristics and anti-complement activities of polysaccharides from Sargassum hemiphyllum.Glycoconjugate journal · 2020Article
- Inhibitory Effects ofViruses · 2020Article
- Preparation and Neuroprotective Activity of Glucuronomannan Oligosaccharides in an MPTP-Induced Parkinson's Model.Marine drugs · 2020Article
- Immunomodulatory Effects of a Low-Molecular Weight Polysaccharide fromMarine drugs · 2020Article
- Protective Effect of Fucoidan against MPPMarine drugs · 2020Article
- Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro.Cell discovery · 2020Article
- Selective Suppression of Cell Growth and Programmed Cell Death-Ligand 1 Expression in HT1080 Fibrosarcoma Cells by Low Molecular Weight Fucoidan Extract.Marine drugs · 2019Article
- Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity.Marine drugs · 2018Article
- Sulfated Hetero-Polysaccharides Protect SH-SY5Y Cells from H₂O₂-Induced Apoptosis by Affecting the PI3K/Akt Signaling Pathway.Marine drugs · 2017Article
- The Structure-Activity Relationship between Marine Algae Polysaccharides and Anti-Complement Activity.Marine drugs · 2015Article
- Structural analysis and anti-complement activity of polysaccharides from Kjellmaniella crsaaifolia.Marine drugs · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A fucoidan extracted from Saccharina japonica was fractionated by anion exchange chromatography. The most complex fraction F0.5 was degraded by dilute sulphuric acid and then separated by use of an activated carbon column. Fraction Y1 was fractionated by anion exchange and gel filtration chromatography while Fraction Y2 was fractionated by gel filtration chromatography. The fractions were determined by ESI-MS and analyzed by ESI-CID-MS/MS. It was concluded that F0.5 had a backbone of alternating 4-linked GlcA and 2-linked Man with the first Man residue from the nonreducing end accidentally sulfated at C6. In addition, F0.5 had a 3-linked glucuronan, in accordance with a previous report by NMR. Some other structural characteristics included GlcA 1→3 Man 1→4 GlcA, Man 1→3 GlcA 1→4 GlcA, Fuc 1→4 GlcA and Fuc 1→3 Fuc. Finally, it was shown that fucose was sulfated at C2 or C4 while galactose was sulfated at C2, C4 or C6.
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