Evidence map›Paper›PMID 23169974›Full record

ArticleThe Journal of infectious diseases2012

Influenza surveillance among children with pneumonia admitted to a district hospital in coastal Kenya, 2007-2010.

Clayton O Onyango, Regina Njeru, Sidi Kazungu, Rachel Achilla, Wallace Bulimo, Stephen R Welch, Patricia A Cane, Rory N Gunson, Laura L Hammitt, J Anthony G Scott and 2 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  14. Continuous Invasion by Respiratory Viruses Observed in Rural Households During a Respiratory Syncytial Virus Seasonal Outbreak in Coastal Kenya.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Clayton O OnyangoKEMRI-Wellcome Trust Research Programme, Kilifi District Hospital, Kilifi, Kenya. conyango@kilifi.kemri-wellcome.org
Regina Njeru
Sidi Kazungu
Rachel Achilla
Wallace Bulimo
Stephen R Welch
Patricia A Cane
Rory N Gunson
Laura L Hammitt
J Anthony G Scott
James A Berkley
D James Nokes
Wellcome Trust · GBHealth Protection Agency · MVKenya Medical Research Institute · KEGartnavel General Hospital · GBUniversity of Oxford · GB

Funding

Wellcome Trust 081186Wellcome Trust 081835Wellcome Trust 084633Wellcome Trust 092654
6 · The paper itself

Abstract

backgroundInfluenza data gaps in sub-Saharan Africa include incidence, case fatality, seasonal patterns, and associations with prevalent disorders.

methodsNasopharyngeal samples from children aged <12 years who were admitted to Kilifi District Hospital during 2007-2010 with severe or very severe pneumonia and resided in the local demographic surveillance system were screened for influenza A, B, and C viruses by molecular methods. Outpatient children provided comparative data.

resultsOf 2002 admissions, influenza A virus infection was diagnosed in 3.5% (71), influenza B virus infection, in 0.9% (19); and influenza C virus infection, in 0.8% (11 of 1404 tested). Four patients with influenza died. Among outpatients, 13 of 331 (3.9%) with acute respiratory infection and 1 of 196 without acute respiratory infection were influenza positive. The annual incidence of severe or very severe pneumonia, of influenza (any type), and of influenza A, was 1321, 60, and 43 cases per 100,000 <5 years of age, respectively. Peak occurrence was in quarters 3-4 each year, and approximately 50% of cases involved infants: temporal association with bacteremia was absent. Hypoxia was more frequent among pneumonia cases involving influenza (odds ratio, 1.78; 95% confidence interval, 1.04-1.96). Influenza A virus subtypes were seasonal H3N2 (57%), seasonal H1N1 (12%), and 2009 pandemic H1N1 (7%).

conclusionsThe burden of influenza was small during 2007-2010 in this pediatric hospital in Kenya. Influenza A virus subtype H3N2 predominated, and 2009 pandemic influenza A virus subtype H1N1 had little impact.

Indexed as

ChildChild, PreschoolFemaleGammainfluenzavirusHospitalizationHospitals, DistrictHumansInfantInfant, NewbornInfluenza A virusInfluenza B virusInfluenza, HumanKenyaMaleNasopharynxPneumonia, Viral

Identifiers

PMID23169974
PMCPMC3502370
OpenAlexW2121636518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.