ArticleAIDS (London, England)2013
Improved employment and education outcomes in households of HIV-infected adults with high CD4 cell counts: evidence from a community health campaign in Uganda.
Article in AIDS (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01864603 (Sustainable East Africa Research in Community Health), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sustainable East Africa Research in Community Health
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sarcopenia in people living with the Human Immunodeficiency Virus: a systematic review and meta-analysis.European journal of clinical nutrition · 2020Pooled it
- Interventions for improving employment outcomes for workers with HIV.The Cochrane database of systematic reviews · 2015Pooled it
- Towards universal voluntary HIV testing and counselling: a systematic review and meta-analysis of community-based approaches.PLoS medicine · 2013Pooled it
- Trial
- Trial
- Trial
- Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+ T-cell counts above 350 cells/μl in rural Uganda.AIDS (London, England) · 2014Trial
- Provider and Patient Perspectives of Rapid ART Initiation and Streamlined HIV Care: Qualitative Insights From Eastern African Communities.Journal of the International Association of Providers of AIDS CareTrial
- Intergenerational spillover effects of antiretroviral therapy in sub-Saharan Africa: a scoping review and future directions for research.BMJ global health · 2023Article
- Significance of initiating antiretroviral therapy in the early stage of HIV infection.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022Article
- Improving access to antiretrovirals in China: economic analyses of dolutegravir in HIV-1 patients.Cost effectiveness and resource allocation : C/E · 2019Article
- Estimating the real-world effects of expanding antiretroviral treatment eligibility: Evidence from a regression discontinuity analysis in Zambia.PLoS medicine · 2018Article
- Socio-economic status and time trends associated with early ART initiation following primary HIV infection in Montreal, Canada: 1996 to 2015.Journal of the International AIDS Society · 2018Article
- Willingness by people living with HIV/AIDS to utilize HIV services provided by Village Health team workers in Kalungu district, central Uganda.African health sciences · 2017Article
- The economic benefits of high CD4 counts among people living with HIV/AIDS in Zambia.Journal of public health (Oxford, England) · 2016Article
- Trends in AIDS Deaths, New Infections and ART Coverage in the Top 30 Countries with the Highest AIDS Mortality Burden; 1990-2013.PloS one · 2015Article
- Treatment as prevention--where next?Current HIV/AIDS reports · 2014Review
- Modeling scenarios for the end of AIDS.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014Article
- Global response to HIV: treatment as prevention, or treatment for treatment?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014Article
- CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda.AIDS (London, England) · 2014Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundThere is limited evidence on the association between socioeconomic outcomes and CD4 counts in populations that include HIV-infected adults who have high CD4 counts or have not been diagnosed. We examined this association among adults in a rural Ugandan parish.
methodsA community health campaign offering diagnostic and treatment services for HIV and other diseases was conducted with Ministry of Health support. Data on campaign participants' education and employment were collected and a detailed household socioeconomic survey was conducted among a subset of participants. Regression analyses were used to assess relationships between CD4 count and employment and education outcomes.
resultsA total of 2323 adults (74% of the community) participated in the campaign; 179 of 2282 (7.8%) tested HIV-positive and 46% were newly diagnosed. Among HIV-infected adults not on antiretroviral therapy (ART), those with CD4 at least 500 worked 6.9 more days/month (P < 0.01; 39% more) and 2.5 more h per day (P < 0.05, 44% more) than those with CD4 less than 200. These effects were not significantly different from the effects for those with CD4 350-499. Children aged 6-11 years in households of adults with CD4 at least 350 did not have significantly different school enrollment rates than children in households of adults with CD4 less than 350, but differences were larger among children aged 12-18 years.
conclusionOutcomes of HIV-infected adults with CD4 at least 350 were better than those of adults with CD4 less than 200 and resembled those of HIV-uninfected adults. The results suggest that early ART initiation may generate economic benefits by preventing a decline in socioeconomic status, but further research is needed to determine the CD4 threshold at which these benefits would be largest.
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