Evidence map›Paper›PMID 23169068›Full record

Trial reportSpine2013

Single- versus multilevel fusion for single-level degenerative spondylolisthesis and multilevel lumbar stenosis: four-year results of the spine patient outcomes research trial.

Yossi Smorgick, Daniel K Park, Kevin C Baker, Jon D Lurie, Tor D Tosteson, Wenyan Zhao, Harry N Herkowitz, Jeffrey S Fischgrund, James N Weinstein

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Spine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04542720 (Decompression Versus Decompression and Fusion for Lumbar Adjacent Segment Disease), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04542720 recruitingnot on this mapstarted 2020, after this paper: background citation

Decompression Versus Decompression and Fusion for Lumbar Adjacent Segment Disease

TypeobservationalSponsorMassachusetts General HospitalRan2020 to 2027Enrolled96ConditionsAdjacent Segment DiseaseArmsObservational: Decompression, Observational: Extension Fusion
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Surgical options for lumbar spinal stenosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. A prospective randomised controlled trial to assess the efficacy of dynamic stabilisation of the lumbar spine with the Wallis ligament.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014
    Trial
  5. Dialysis status and its association with complications, discharge outcomes, and costs after multilevel lumbar fusion: a national analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yossi SmorgickDepartment of Orthopedic Surgery, William Beaumont Hospital, Royal Oak, MI 48073, USA. Noam_Yossi@yahoo.com
Daniel K Park
Kevin C Baker
Jon D Lurie
Tor D Tosteson
Wenyan Zhao
Harry N Herkowitz
Jeffrey S Fischgrund
James N Weinstein
Orthopedic One · USDartmouth Institute for Health Policy and Clinical Practice · USBeaumont Hospital, Royal Oak · USDartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIALU01AR045444 · NIAMS · DARTMOUTH COLLEGE · PI WEINSTEIN, JAMES N · 1999 to 2013
$20.8M
NCI NIH HHS P30 CA023108NIAMS NIH HHS U01 AR045444
6 · The paper itself

Abstract

STUDY

designA subanalysis study.

objectiveTo compare surgical outcomes and complications of multilevel decompression and single-level fusion with multilevel decompression and multilevel fusion for patients with multilevel lumbar stenosis and single-level degenerative spondylolisthesis (DS). SUMMARY OF BACKGROUND DATA: In patients with DS who are treated surgically, decompression and fusion provide a better clinical outcome than decompression alone. Surgical treatment for multilevel lumbar stenosis and DS typically includes decompression and fusion of the spondylolisthesis segment and decompression with or without fusion for the other stenotic segments. To date, no study has compared the results of these 2 surgical options for single-level DS with multilevel stenosis.

methodsThe results from a multicenter randomized and observational study, the Spine Patient Outcomes Research Trial comparing multilevel decompression and single-level fusion and multilevel decompression and multilevel fusion for spinal stenosis with spondylolisthesis, were analyzed. The primary outcome measures were the bodily pain and physical function scales of the Medical Outcomes Study 36-item Short-Form General Health Survey (SF-36) and the modified Oswestry Disability Index at 1, 2, 3, and 4 years postoperatively. Secondary analysis consisted of stenosis bothersomeness index, low back pain bothersomeness, leg pain, patient satisfaction, and self-rated progress.

resultsOverall, 207 patients were enrolled for the study, 130 had multlilevel decompression with 1 level fusion and 77 patients had multilevel decompression and multilevel fusion. For all primary and secondary outcome measures, there were no statistically significant differences in surgical outcomes between the 2 surgical techniques. However, operative time and intraoperative blood loss were significantly higher in the multilevel fusion group.

conclusionDecompression and single-level fusion and decompression and multilevel fusion provide similar outcomes in patients with multilevel lumbar stenosis and single-level DS.

Indexed as

AgedFemaleFollow-Up StudiesHumansKaplan-Meier EstimateLumbar VertebraeMaleMiddle AgedPatient Outcome AssessmentQuality of LifeSpinal FusionSpinal StenosisSpondylolisthesisSurveys and Questionnaires

Identifiers

PMID23169068
PMCPMC3757550
OpenAlexW2004765604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.