ReviewCanadian journal of gastroenterology = Journal canadien de gastroenterologie2012
Evaluation and management of skeletal health in celiac disease: position statement.
Review in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- A systematic review of intervention thresholds based on FRAX : A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation.Archives of osteoporosis · 2016Pooled it
- Bone Density and Fractures in HIV-infected Postmenopausal Women: A Systematic Review.The Journal of the Association of Nurses in AIDS Care : JANACPooled it
- High prevalence of laboratory abnormalities indicative of secondary osteoporosis detected by systematic testing.JBMR plus · 2025Article
- Genetic, Immunological, Dietary, Gut Microbiota, and Environmental Determinants of Osteoporosis in the Course of Celiac Disease: Which Factor Plays the First Violin in This Orchestra?Calcified tissue international · 2024Review
- Vitamin D and malabsorptive gastrointestinal conditions: A bidirectional relationship?Reviews in endocrine & metabolic disorders · 2023Review
- Osteoporosis and Celiac Disease: Updates and Hidden Pitfalls.Nutrients · 2023Review
- Celiac disease and bone.Archives of endocrinology and metabolism · 2022Review
- Review article: Follow-up of coeliac disease.Alimentary pharmacology & therapeutics · 2022Review
- Review article: Systemic consequences of coeliac disease.Alimentary pharmacology & therapeutics · 2022Review
- Follow-up practices for children and adolescents with celiac disease: results of an international survey.European journal of pediatrics · 2022Article
- Bone Fragility in Gastrointestinal Disorders.International journal of molecular sciences · 2022Review
- Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet.Nutrients · 2021Article
- Updates on bone health in children with gastrointestinal diseases.Annals of pediatric endocrinology & metabolism · 2020Article
- Survey of the initial management of celiac disease antibody tests by ordering physicians.BMC pediatrics · 2019Observational
- Risk factors associated with osteoporosis in a cohort of prospectively diagnosed adult coeliac patients.United European gastroenterology journal · 2018Article
- Review
- Management of bone health in patients with celiac disease: Practical guide for clinicians.Canadian family physician Medecin de famille canadien · 2018Review
- Update on Bone Health in Pediatric Chronic Disease.Endocrinology and metabolism clinics of North America · 2016Review
- Bone and Celiac Disease.Current osteoporosis reports · 2016Review
- Practical insights into gluten-free diets.Nature reviews. Gastroenterology & hepatology · 2015Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo review the evaluation and management of skeletal health in patients with celiac disease (CD), and to make recommendations on screening, diagnosis, treatment and follow-up of low bone mineral density (BMD) in CD patients.
methodsA multidisciplinary team developed clinically relevant questions for review. An electronic search of the literature was conducted using the MEDLINE and EMBASE databases from 1996 to 2010. All original studies, reviews and guidelines, both pediatric and adult, were included. A document summarizing the results of the review and proposed recommendations was prepared and underwent multiple revisions until consensus was reached.
resultsAt diagnosis, approximately one-third of adult CD patients have osteoporosis, one-third have osteopenia and one-third have normal BMD. Children with CD have low bone mass at diagnosis. Adult and pediatric CD patients are at increased risk of fractures. DISCUSSION: For adults, serum calcium, albumin, 25(OH) vitamin D3, parathyroid hormone and 24 h urine calcium testing should be performed at diagnosis; patients with 'classic' CD and those at risk for osteoporosis should undergo a dual x-ray absorptiometry scan. An abnormal baseline dual x-ray absorptiometry scan should be repeated one to two years after initiation of a gluten-free diet (GFD). For children, BMD should be assessed one year after diagnosis if GFD adherence is not strict. A GFD is the most important treatment for bone loss. Supplemental antiresorptives may be justified in those who remain at high fracture risk (eg, postmenopausal women, older men) after implementation of a GFD.
conclusionCurrent evidence does not support the screening of all CD patients for low BMD at diagnosis. Follow-up BMD assessment should be performed one to two years after initiation of a GFD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.