ArticlePloS one2012
Contact investigation in households of patients with tuberculosis in Hanoi, Vietnam: a prospective cohort study.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Symptom- and chest-radiography screening for active pulmonary tuberculosis in HIV-negative adults and adults with unknown HIV status.The Cochrane database of systematic reviews · 2022Pooled it
- Prevention of tuberculosis in household members: estimates of children eligible for treatment.Bulletin of the World Health Organization · 2019Pooled it
- Barriers to adherence with tuberculosis contact investigation in six provinces of Vietnam: a nested case-control study.BMC infectious diseases · 2015Trial
- Trial
- Cachexia in tuberculosis in South-East Asian and African regions: knowledge gaps and untapped opportunities.Annals of medicine and surgery (2012) · 2024Review
- Comparison of the yield of two tuberculosis screening approaches among household contacts in a community setting of Silti Zone, Central Ethiopia: a prospective cohort study.BMC pulmonary medicine · 2024Article
- Assessment of Family Tuberculosis Contact Screening Practice and its Associated Factors Among Pulmonary Tuberculosis Positive Patients in South Wollo Zone, Amhara Region, Ethiopia.International journal of public health · 2023Article
- Tuberculosis in household contacts of tuberculosis patients in sub-Saharan African countries: A systematic review and meta-analysis.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Review
- Tuberculosis contact investigation in African Portuguese-speaking countries at End TB Strategy era: a scoping review.BMJ open · 2022Article
- Resistance to Mycobacterium tuberculosis Infection Among Household Contacts: A Multinational Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Decline of Tuberculosis Burden in Vietnam Measured by Consecutive National Surveys, 2007-2017.Emerging infectious diseases · 2021Article
- Yield of household contact investigation of patients with pulmonary tuberculosis in southern Ethiopia.BMC public health · 2020Article
- Article
- High incidence and low case detection rate among contacts of tuberculosis cases in Shanghai, China.BMC infectious diseases · 2019Article
- A population-based tuberculosis contact investigation in the country of Georgia.Public health action · 2018Article
- Prevalence and Incidence of Smear-Positive Pulmonary Tuberculosis in the Hetosa District of Arsi Zone, Oromia Regional State of Central Ethiopia.BMC infectious diseases · 2017Article
- Tuberculosis case finding in first-degree relative contacts not living with index tuberculosis cases in Kampala, Uganda.Clinical epidemiology · 2015Article
- Immunoendocrine interactions during HIV-TB coinfection: implications for the design of new adjuvant therapies.BioMed research international · 2015Review
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
settingExisting tuberculosis control strategies in Vietnam are based on symptomatic patients attending health services for investigation. This approach has not resulted in substantial reductions in the prevalence of tuberculosis disease, despite the National Tuberculosis Program achieving high treatment completion rates. Alternative approaches are being considered.
objectiveTo determine the feasibility and yield of contact investigation in households of patients with smear positive pulmonary tuberculosis among household members of tuberculosis patients in Hanoi, Vietnam.
methodsHousehold contacts of patients with smear positive pulmonary tuberculosis were recruited at four urban and rural District Tuberculosis Units in Hanoi. Clinical and radiological screening was conducted at baseline, six months and 12 months. Sputum microscopy and culture was performed in contacts suspected of having tuberculosis. MIRU-VNTR molecular testing was used to compare the strains of patients and their contacts with disease.
resultsAmong 545 household contacts of 212 patients, four were diagnosed with tuberculosis at baseline (prevalence 734 cases per 100,000 persons, 95% CI 17-1451) and one was diagnosed with tuberculosis during the subsequent 12 months after initial screening (incidence 180 cases per 100,000 person-years, 95% CI 44-131). Two of these cases were culture positive for M. tuberculosis and both had identical or near-identical MIRU-VNTR strain types.
conclusionHousehold contacts of patients with potentially infectious forms of tuberculosis have a high prevalence of disease. Household contact investigation is feasible in Vietnam. Further research is required to investigate its effectiveness.
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