Evidence map›Paper›PMID 23166683›Full record

ArticlePloS one2012

Beat-to-beat vectorcardiographic analysis of ventricular depolarization and repolarization in myocardial infarction.

Muhammad A Hasan, Derek Abbott, Mathias Baumert

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

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  7. Toward a novel semi-invasive activation mapping tool for the diagnosis of supraventricular arrhythmias from the esophagus.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Muhammad A HasanSchool of Electrical & Electronic Engineering, The University of Adelaide, Adelaide, Australia.
Derek Abbott
Mathias Baumert
University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIncreased beat-to-beat variability in the QT interval has been associated with heart disease and mortality. The purpose of this study was to investigate the beat-to-beat spatial and temporal variations of ventricular depolarization and repolarization in vectorcardiogram (VCG) for characterising myocardial infarction (MI) patients.

methodsStandard 12-lead ECGs of 84 MI patients (22 f, 63±12 yrs; 62 m, 56±10 yrs) and 69 healthy subjects (17 f, 42±18 yrs; 52 m, 40±13 yrs) were investigated. To extract the beat-to-beat QT intervals, a template-matching algorithm and the singular value decomposition method have been applied to synthesise the ECG data to VCG. Spatial and temporal variations in the QRS complex and T-wave loops were studied by investigating several descriptors (point-to-point distance variability, mean loop length, T-wave morphology dispersion, percentage of loop area, total cosine R-to-T).

resultsPoint-to-point distance variability of QRS and T-loops (0.13±0.04 vs. 0.10±0.04, p< 0.0001 and 0.16±0.07 vs. 0.13±0.06, p< 0.05) were significantly larger in the MI group than in the control group. The average T-wave morphology dispersion was significantly higher in the MI group than in the control group (62°±8° vs. 38°±16°, p< 0.0001). Further, its beat-to-beat variability appeared significantly lower in the MI group than in the control group (12°±5° vs. 15°±6°, p< 0.005). Moreover, the average percentage of the T-loop area was found significantly lower in the MI group than the controls (46±17 vs. 55±15, p< 0.001). Finally, the average and beat-to-beat variability of total cosine R-to-T were not found statistically significant between both groups.

conclusionsBeat-to-beat assessment of VCG parameters may have diagnostic attributes that might help in identifying MI patients.

Indexed as

VectorcardiographyAdultAgedCase-Control StudiesElectrocardiographyFemaleHeart VentriclesHumansMaleMiddle AgedMyocardial Infarction

Identifiers

PMID23166683
PMCPMC3498118
OpenAlexW2098651122

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.