ArticlePLoS genetics2012
A novel human-infection-derived bacterium provides insights into the evolutionary origins of mutualistic insect-bacterial symbioses.
Article in PLoS genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
- The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts.Molecular biology and evolution · 2026Article
- Phylogenetically diverse MucoralesMicrobial genomics · 2026Article
- Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe-Host-Interaction With the Most Complex Human Commensal, Demodex folliculorum.Environmental microbiology reports · 2026Article
- Complementary Microscopic and Metabarcoding Studies Allow for a Better Understanding of the Symbiotic Microbiome of Leafhopper Species Iassus lanio (Hemiptera, Cicadellidae).Microbial ecology · 2026Article
- Contrasting Genomic Trajectories of Bartonellaceae Symbionts of Planthoppers.Genome biology and evolution · 2025Article
- Evolutionary dynamics of obligate endosymbiosis in the psyllid genus Cacopsylla.Communications biology · 2025Article
- Evolution of the Plant-Associated Pantoea was Accompanied by Plasmid Domestication Events.Molecular biology and evolution · 2025Article
- Article
- Independent and repeated acquisition ofRoyal Society open science · 2025Article
- Effect of Oceanic Islands on an Insect Symbiont Genome in Transition to a Host-Restricted Lifestyle.Genome biology and evolution · 2025Article
- From eggs to guts: Symbiotic association of Sodalis nezarae sp. nov. with the Southern green shield bug Nezara viridula.FEMS microbiology ecology · 2025Article
- Adaptive pangenomic remodeling in the Azolla cyanobiont amid a transient microbiome.The ISME journal · 2025Article
- Facultatively intrabacterial localization of a planthopper endosymbiont as an adaptation to its vertical transmission.mSystems · 2024Article
- With a little help from my friends: the roles of microbial symbionts in insect populations and communities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Stochasticity, determinism, and contingency shape genome evolution of endosymbiotic bacteria.Nature communications · 2024Article
- Cereal weevils' antimicrobial peptides: at the crosstalk between development, endosymbiosis and immune response.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Comparative genomic analysis of symbiotic and free-livingApplied and environmental microbiology · 2024Article
- Intracellular symbiont Symbiodolus is vertically transmitted and widespread across insect orders.The ISME journal · 2024Article
- Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.Microbiome · 2023Article
- Genome Comparison Reveals Inversions and Alternative Evolutionary History of Nutritional Endosymbionts in Planthoppers (Hemiptera: Fulgoromorpha).Genome biology and evolution · 2023Article
33 more citing papers are in PubMed but not listed here.
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9 authors.
Funding
Abstract
Despite extensive study, little is known about the origins of the mutualistic bacterial endosymbionts that inhabit approximately 10% of the world's insects. In this study, we characterized a novel opportunistic human pathogen, designated "strain HS," and found that it is a close relative of the insect endosymbiont Sodalis glossinidius. Our results indicate that ancestral relatives of strain HS have served as progenitors for the independent descent of Sodalis-allied endosymbionts found in several insect hosts. Comparative analyses indicate that the gene inventories of the insect endosymbionts were independently derived from a common ancestral template through a combination of irreversible degenerative changes. Our results provide compelling support for the notion that mutualists evolve from pathogenic progenitors. They also elucidate the role of degenerative evolutionary processes in shaping the gene inventories of symbiotic bacteria at a very early stage in these mutualistic associations.
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