ArticleInternational journal of nanomedicine2012
Polyacrylonitrile nanofibers coated with silver nanoparticles using a modified coaxial electrospinning process.
Article in International journal of nanomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Xylitol Modification of Electrospun Polymer Scaffolds: Impact on Physicochemical and Antibacterial Properties.Polymers · 2025Article
- Composite Nanoarchitectonics of Electrospun Piezoelectric PVDF/AgNPs for Biomedical Applications, Including Breast Cancer Treatment.Materials (Basel, Switzerland) · 2024Article
- Silver-doped bioactive glass fibres as a potential treatment for wound-associated bacterial biofilms.Biofilm · 2023Article
- Optimization of process parameters for fabrication of electrospun nanofibers containing neomycin sulfate andDrug delivery · 2022Article
- Synthesis of Electrospun PAN/TiOACS omega · 2022Article
- Review
- Review
- Electrospun Environment Remediation Nanofibers Using Unspinnable Liquids as the Sheath Fluids: A Review.Polymers · 2020Review
- Recent developments in polymeric electrospun nanofibrous membranes for seawater desalination.RSC advances · 2018Review
- Electrospun Silver Coated Polyacrylonitrile Membranes for Water Filtration Applications.Membranes · 2018Article
- The potential applications of fibrin-coated electrospun polylactide nanofibers in skin tissue engineering.International journal of nanomedicine · 2016Article
- Sustained release of vancomycin from novel biodegradable nanofiber-loaded vascular prosthetic grafts: in vitro and in vivo study.International journal of nanomedicine · 2015Article
- Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies.International journal of nanomedicine · 2015Article
- CD44(+)/CD24(-) breast cancer cells exhibit phenotypic reversion in three-dimensional self-assembling peptide RADA16 nanofiber scaffold.International journal of nanomedicine · 2015Article
- Fabrication and characterization of anisotropic nanofiber scaffolds for advanced drug delivery systems.International journal of nanomedicine · 2014Article
- Effect of silk fibroin nanofibers containing silver sulfadiazine on wound healing.International journal of nanomedicine · 2014Article
- Silver nanoparticle/chitosan oligosaccharide/poly(vinyl alcohol) nanofibers as wound dressings: a preclinical study.International journal of nanomedicine · 2013Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this investigation was to develop a new class of antibacterial material in the form of nanofibers coated with silver nanoparticles (AgNPs) using a modified coaxial electrospinning approach. Through manipulation of the distribution on the surface of nanofibers, the antibacterial effect of Ag can be improved substantially.
methodsUsing polyacrylonitrile (PAN) as the filament-forming polymer matrix, an electrospinnable PAN solution was prepared as the core fluid. A silver nitrate (AgNO₃) solution was exploited as sheath fluid to carry out the modified coaxial electrospinning process under varied sheath-to-core flow rate ratios.
resultsScanning electron microscopy and transmission electron microscopy demonstrated that the sheath AgNO₃ solution can take a role in reducing the nanofibers' diameters significantly, a sheath-to-core flow rate ratio of 0.1 and 0.2 resulting in PAN nanofibers with diameters of 380 ± 110 nm and 230 ± 70 nm respectively. AgNPs are well distributed on the surface of PAN nanofibers. The antibacterial experiments demonstrated that these nanofibers show strong antimicrobial activities against Bacillus subtilis Wb800, and Escherichia coli dh5α.
conclusionCoaxial electrospinning with AgNO₃ solution as sheath fluid not only facilitates the electrospinning process, providing nanofibers with reduced diameters, but also allows functionalization of the nanofibers through coating with functional ingredients, effectively ensuring that the active antibacterial component is on the surface of the material, which leads to enhanced activity. We report an example of the systematic design, preparation, and application of a novel type of antibacterial material coated with AgNPs via a modified coaxial electrospinning methodology.
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