ArticleJournal of Korean medical science2012
Membranous nephropathy in a 13-year-old boy with common variable immunodeficiency.
Article in Journal of Korean medical science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Renal Manifestations of Common Variable Immunodeficiency.Kidney360 · 2020Article
- End-stage renal disease secondary to anti-glomerular basement membrane disease in a child with common variable immunodeficiency.Clinical nephrology. Case studies · 2019Article
- Novel Heterozygous Mutation inFrontiers in pediatrics · 2019Article
- Membranous Nephropathy in a Patient With Common Variable Immune Deficiency.Kidney international reports · 2018Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Various forms of hypogammaglobulinemia can occur in patients with autoimmune diseases and vice versa. We report a 13-yr-old boy with membranous nephropathy and common variable immunodeficiency. He presented with the nephrotic syndrome, pneumonia with bronchiectasis, and profound hypogammaglobulinemia. Renal biopsy showed diffusely thickened glomerular capillary walls with 'spikes' suggesting a membranous nephropathy. Secondary causes were ruled out by laboratory studies; however, heavy proteinuria persisted with steroid therapy. Cyclosporine and intravenous immunoglobulin were added, and the patient was discharged with decreased proteinuria. Hypogammaglobulinemia may have a deleterious impact on the immune dysregulation in some patients with membranous nephropathy.
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