ArticleAmerican journal of primatology2013
Single-nucleotide polymorphisms reveal patterns of allele sharing across the species boundary between rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaques.
Article in American journal of primatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Pandemic 1918 Influenza Virus Does Not Cause Lethal Infection in Rhesus or Cynomolgus Macaques.Journal of virology · 2022Article
- Article
- Population Structure of Macaca fascicularis aurea, and their Genetic Relationships with M. f. fascicularis and M. mulatta Determined by 868 RADseq-Derived Autosomal SNPs-A consideration for biomedical research.Journal of medical primatology · 2022Article
- Genome-wide analysis reveals signatures of complex introgressive gene flow in macaques (genusZoological research · 2021Article
- Genomic Copy Number Variation Study of Nine Macaca Species Provides New Insights into Their Genetic Divergence, Adaptation, and Biomedical Application.Genome biology and evolution · 2020Article
- Review
- Comparative genome-wide survey of single nucleotide variation uncovers the genetic diversity and potential biomedical applications among six Macaca species.International journal of molecular sciences · 2018Article
- DNA-based Determination of Ancestry in Cynomolgus Macaques (Journal of the American Association for Laboratory Animal Science : JAALAS · 2018Article
- Ancestry, Plasmodium cynomolgi prevalence and rhesus macaque admixture in cynomolgus macaques (Macaca fascicularis) bred for export in Chinese breeding farms.Journal of medical primatology · 2017Article
- Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- A novel strain of cynomolgus macaque cytomegalovirus: implications for host-virus co-evolution.BMC genomics · 2016Article
- An SNP marker at the STAT6 locus can identify the hybrids between rhesus (Macaca mulatta) and long-tailed macaques (M. fascicularis) in Thailand: a rapid and simple screening method and its application.Primates; journal of primatology · 2016Article
- Mitogenomic phylogeny of the common long-tailed macaque (Macaca fascicularis fascicularis).BMC genomics · 2015Article
- Use of genome-wide heterospecific single-nucleotide polymorphisms to estimate linkage disequilibrium in rhesus and cynomolgus macaques.Comparative medicine · 2015Article
- Examining the species-specificity of rhesus macaque cytomegalovirus (RhCMV) in cynomolgus macaques.PloS one · 2015Article
- Mitogenomics of the Old World monkey tribe Papionini.BMC evolutionary biology · 2014Article
- A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques.American journal of physical anthropology · 2014Article
- The genetic composition of populations of cynomolgus macaques (Macaca fascicularis) used in biomedical research.Journal of medical primatology · 2013Article
- Nonhuman primate models in the genomic era: a paradigm shift.ILAR journal · 2013Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Both phenotypic and genetic evidence for asymmetric hybridization between rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques has been observed in the region of Indochina where both species are sympatric. The large-scale sharing of major histocompatibility complex (MHC) class II alleles between the two species in this region supports the hypothesis that genes, and especially genes involved in immune response, are being transferred across the species boundary. This differential introgression has important implications for the incorporation of cynomolgus macaques of unknown geographic origin in biomedical research protocols. Our study found that for 2,808 single-nucleotide polymorphism (SNP) markers, the minor allele frequencies (MAF) and observed heterozygosity calculated from a sample of Vietnamese cynomolgus macaques was significantly different from those calculated from samples of both Chinese rhesus and Indonesian cynomolgus macaques. SNP alleles from Chinese rhesus macaques were overrepresented in a sample of Vietnamese cynomolgus macaques relative to their Indonesian conspecifics and located in genes functionally related to the primary immune system. These results suggest that Indochinese cynomolgus macaques represent a genetically and immunologically distinct entity from Indonesian cynomolgus macaques.
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