Evidence map›Paper›PMID 23165475›Full record

ArticleChemical communications (Cambridge, England)2013

Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.

Pil Seok Chae, Rohini R Rana, Kamil Gotfryd, Søren G F Rasmussen, Andrew C Kruse, Kyung Ho Cho, Stefano Capaldi, Emil Carlsson, Brian Kobilka, Claus J Loland and 5 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Glyco-Steroidal Amphiphiles (GSAs) for Membrane Protein Structural Study.Chembiochem : a European journal of chemical biology · 2022
    Article
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  11. Article
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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Pil Seok ChaeDepartment of Bionano Engineering, Hanyang University, Ansan, 426-791, Korea. pchae@hanyang.ac.kr
Rohini R Rana
Kamil Gotfryd
Søren G F Rasmussen
Andrew C Kruse
Kyung Ho Cho
Stefano Capaldi
Emil Carlsson
Brian Kobilka
Claus J Loland
Ulrik Gether
Surajit Banerjee
Bernadette Byrne
John K Lee
Samuel H Gellman
Imperial College London · GBStanford University · USUniversity of Copenhagen · DKHanyang University · KRArgonne National Laboratory · USUniversity of Minnesota · USUniversity of Wisconsin–Madison · US

Funding

THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATIONR01NS028471 · NINDS · STANFORD UNIVERSITY · PI KOBILKA, BRIAN K · 1990 to 2021
$6.7M
Synthesis/evaluation of novel surfactants for membrane protein structural biologyP01GM075913 · NIGMS · UNIVERSITY OF CHICAGO · PI LAIBLE, PHILIP D · 2005 to 2009
$4.2M
Beta2 Adrenoceptor Structure and Mechanism of ActivationR37NS028471 · NINDS · STANFORD UNIVERSITY · PI KOBILKA, BRIAN K · 2005 to 2011
$3.9M
NIGMS NIH HHS P01 GM075913NIGMS NIH HHS P01 GM75913NINDS NIH HHS R01 NS028471NINDS NIH HHS R37 NS028471
6 · The paper itself

Abstract

The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

Indexed as

DetergentsGlucoseGlycolsMembrane ProteinsProtein StabilityRhodobacter capsulatusDetergentsGlucoseGlycolsMembrane Proteins

Identifiers

PMID23165475
PMCPMC3578972
OpenAlexW1975641708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.