Evidence map›Paper›PMID 23165178›Full record

ReviewInsect biochemistry and molecular biology2013

Insect microRNAs: biogenesis, expression profiling and biological functions.

Keira Lucas, Alexander S Raikhel

Open access · greenAbstract readReview
In one paragraph

Review in Insect biochemistry and molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 201 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. De Novo miRNAs fromInsects · 2024
    Article
  10. Article
  11. Article
  12. microRNA maintains nutrient homeostasis in the symbiont-host interaction.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. MiR-130c-5p targets the SHVVFrontiers in immunology · 2024
    Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Keira LucasDepartment of Entomology, University of California Riverside, Riverside, CA 92521, USA. kneum001@ucr.edu
Alexander S Raikhel
University of California, Riverside · US

Funding

MOLECULAR BASIS OF ECDYSTEROID ACTION IN THE MOSQUITOR01AI036959 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI RAIKHEL, ALEXANDER SIMEON, ROY, SOURAV · 1995 to 2022
$10.0M
The role of mosquito microRNAs in blood digestion.R01AI113729 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI RAIKHEL, ALEXANDER SIMEON · 2014 to 2023
$4.1M
NIAID NIH HHS 2R01 AI036959NIAID NIH HHS R01 AI036959NIAID NIH HHS R01 AI113729
6 · The paper itself

Abstract

MicroRNAs (miRNA) are a class of endogenous regulatory RNA molecules 21-24 nucleotides in length that modulate gene expression at the post-transcriptional level via base pairing to target sites within messenger RNAs (mRNA). Typically, the miRNA "seed sequence" (nucleotides 2-8 at the 5' end) binds complementary seed match sites within the 3' untranslated region of mRNAs, resulting in either translational inhibition or mRNA degradation. MicroRNAs were first discovered in Caenorhabditis elegans and were shown to be involved in the timed regulation of developmental events. Since their discovery in the 1990s, thousands of potential miRNAs have since been identified in various organisms through small RNA cloning methods and/or computational prediction, and have been shown to play functionally important roles of gene regulation in invertebrates, vertebrates, plants, fungi and viruses. Numerous functions of miRNAs identified in Drosophila melanogaster have demonstrated a great significance of these regulatory molecules. However, elucidation of miRNA roles in non-drosophilid insects presents a challenging and important task.

Indexed as

RNA InterferenceAnimalsGene Expression ProfilingInsectaMicroRNAsMicroRNAs

Identifiers

PMID23165178
PMCPMC3534889
OpenAlexW1999309921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.