Evidence map›Paper›PMID 23163647›Full record

ArticleExperimental dermatology2012

Unravelling hair follicle-adipocyte communication.

Barbara Schmidt, Valerie Horsley

Open access · bronzeAbstract read
In one paragraph

Article in Experimental dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Delivery Strategies of siRNA Therapeutics for Hair Loss Therapy.International journal of molecular sciences · 2024
    Review
  6. Article
  7. [Research progress in regulation of hair growth by dermal adipose tissue].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Barbara SchmidtDepartment of Molecular, Cell and Developmental Biology, Yale Stem Cell Center, Yale University, New Haven, CT, USA.
Valerie Horsley
Yale University · US

Funding

Extrinsic Regulation of Epidermal HomeostatasisR01AR060295 · NIAMS · YALE UNIVERSITY · PI HORSLEY, VALERIE · 2011 to 2016
$2.2M
Extrinsic Regulation that Regulate Skin HomeostasisR56AR060295 · NIAMS · YALE UNIVERSITY · PI HORSLEY, VALERIE · 2018 to 2018
$481k
NIAMS NIH HHS AR060295NIAMS NIH HHS R01 AR060295NIAMS NIH HHS R56 AR060295
6 · The paper itself

Abstract

Here, we explore the established and potential roles for intradermal adipose tissue in communication with hair follicle biology. The hair follicle delves deep into the rich dermal macroenvironment as it grows to maturity where it is surrounded by large lipid-filled adipocytes. Intradermal adipocytes regenerate with faster kinetics than other adipose tissue depots and in parallel with the hair cycle, suggesting an interplay exists between hair follicle cells and adipocytes. While adipocytes have well-established roles in metabolism and energy storage, until recently, they were overlooked as niche cells that provide important growth signals to neighbouring skin cells. We discuss recent data supporting adipocytes as niche cells for the skin and skin pathologies that may be related to alterations in skin adipose tissue defects.

Indexed as

Skin Physiological PhenomenaAdipocytesAlopeciaAnimalsCell CommunicationDisease Models, AnimalHair FollicleHumansHypertrichosisMiceRegeneration

Identifiers

PMID23163647
PMCPMC3507425
OpenAlexW2019551443

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.