Evidence map›Paper›PMID 23162710›Full record

ArticleBiomedical optics express2012

Goniometric measurements of thick tissue using Monte Carlo simulations to obtain the single scattering anisotropy coefficient.

Gunnsteinn Hall, Steven L Jacques, Kevin W Eliceiri, Paul J Campagnola

Abstract read
In one paragraph

Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Microscope objective based 4Biomedical optics express · 2017
    Article
  10. Article
  11. Article
  12. Article
  13. Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Modeling Light Scattering in Tissue as Continuous Random Media Using a Versatile Refractive Index Correlation Function.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gunnsteinn HallDepartment of Biomedical Engineering & Laboratory of Optical and Computational Instrumentation, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Steven L Jacques
Kevin W Eliceiri
Paul J Campagnola

Funding

Development of The Prairie Technologies MPLSM to image cancer models in vivoR01CA136590 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CAMPAGNOLA, PAUL J, KEELY, PATRICIA J · 2009 to 2013
$2.4M
A Spectral/Lifetime Microscope for in vivo StudiesR01EB000184 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI WHITE, JOHN GRAHAM · 2002 to 2006
$1.9M
NCI NIH HHS R01 CA136590NIBIB NIH HHS R01 EB000184
6 · The paper itself

Abstract

The scattering anisotropy, g, of tissue can be a powerful metric of tissue structure, and is most directly measured via goniometry and fitting to the Henyey-Greenstein phase function. We present a method based on an independent attenuation measurement of the scattering coefficient along with Monte Carlo simulations to account for multiple scattering, allowing the accurate determination of measurement of g for tissues of thickness within the quasi-ballistic regime. Simulations incorporating the experimental geometry and bulk optical properties show that significant errors occur in extraction of g values, even for tissues of thickness less than one scattering length without modeling corrections. Experimental validation is provided by determination of g in mouse muscle tissues and it is shown that the obtained values are independent of thickness. In addition we present a simple deconvolution-based method and show that it provides excellent estimates for high anisotropy values (above 0.95) when coupled with an independent attenuation measurement.

Indexed as

(120.5820) Scattering measurements(170.3660) Light propagation in tissues(170.6935) Tissue characterization(290.0290) Scattering(290.4210) Multiple scattering(290.5820) Scattering measurements

Identifiers

PMID23162710
PMCPMC3493220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.