Evidence map›Paper›PMID 23162675›Full record

ArticleWater quality, exposure, and health2012

Modeling the combined influence of host dispersal and waterborne fate and transport on pathogen spread in complex landscapes.

Adam N Akullian, Ding Lu, Julia Z McDowell, George M Davis, Robert C Spear, Justin V Remais

Abstract read
In one paragraph

Article in Water quality, exposure, and health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Adam N AkullianUniversity of Washington, School of Public Health and Community Medicine, Department of Epidemiology, Box 357236, Seattle, WA 98195, USA, Tel.: +1 206 897 6396.
Ding Lu
Julia Z McDowell
George M Davis
Robert C Spear
Justin V Remais
Emory University · USBerkeley Public Health Division · USSichuan Center for Disease Control and Prevention · CNUniversity of Washington · USWashington University Medical Center · US

Funding

Determinants of Schistosomiasis Re-emergenceR01AI068854 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI SPEAR, ROBERT C · 2007 to 2011
$2.3M
Models for improving surveillance of environmentally-mediated infectious diseasesK01AI091864 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI REMAIS, JUSTIN V · 2011 to 2015
$643k
NIAID NIH HHS K01 AI091864NIAID NIH HHS R01 AI068854
6 · The paper itself

Abstract

Environmental models, often applied to questions on the fate and transport of chemical hazards, have recently become important in tracing certain environmental pathogens to their upstream sources of contamination. These tools, such as first order decay models applied to contaminants in surface waters, offer promise for quantifying the fate and transport of pathogens with multiple environmental stages and/or multiple hosts, in addition to those pathogens whose environmental stages are entirely waterborne. Here we consider the fate and transport capabilities of the human schistosome Schistosoma japonicum, which exhibits two waterborne stages and is carried by an amphibious intermediate snail host. We present experimentally-derived dispersal estimates for the intermediate snail host and fate and transport estimates for the passive downstream diffusion of cercariae, the waterborne, human-infective parasite stage. Using a one dimensional advective transport model exhibiting first-order decay, we simulate the added spatial reach and relative increase in cercarial concentrations that dispersing snail hosts contribute to downstream sites. Simulation results suggest that snail dispersal can substantially increase the concentrations of cercariae reaching downstream locations, relative to no snail dispersal, effectively putting otherwise isolated downstream sites at increased risk of exposure to cercariae from upstream sources. The models developed here can be applied to other infectious diseases with multiple life-stages and hosts, and have important implications for targeted ecological control of disease spread.

Identifiers

PMID23162675
PMCPMC3496273
OpenAlexW2043522459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.