ArticleFrontiers in neurology2012
The epidemiology and clinical manifestations of dysexecutive syndrome in Parkinson's disease.
Article in Frontiers in neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 44 citations in OpenAlex.
- A quick test of cognitive speed can predict development of dementia in Parkinson's disease.Scientific reports · 2019Trial
- Improved cognitive flexibility after high-intensity interval training (HIIT) in individuals with Parkinson's disease: a pilot randomized controlled trial.Frontiers in rehabilitation sciences · 2026Article
- Investigate the differences in executive functions and behavioral baseline indicators of Parkinson's disease model mice based on the five - choice serial reaction time task.Laboratory animal research · 2025Article
- Executive Functioning Profiles in Children with Neurodevelopmental Disorders.Behavioral sciences (Basel, Switzerland) · 2025Article
- Psychometric validation for a brand-new tool for the assessment of executive functions using 360° technology.Scientific reports · 2023Article
- The assessment of executive functions to test the integrity of the nigrostriatal network: A pilot study.Frontiers in psychology · 2023Article
- Approach to Cognitive Impairment in Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Review
- Association Between Behavioral Dysexecutive Syndrome and the Health-Related Quality of Life Among Stroke Survivors.Frontiers in psychiatry · 2020Article
- Mild cognitive impairment in Parkinson's disease: a distinct clinical entity?Translational neurodegeneration · 2017Review
- Virtual multiple errands test (VMET): a virtual reality-based tool to detect early executive functions deficit in Parkinson's disease.Frontiers in behavioral neuroscience · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This mini-review summarizes the evidence of the cognitive and behavioral features of dysexecutive syndrome in Parkinson's disease (PD). Deficits in response inhibition, set-shifting, mental flexibility, and strategy have been frequently described from the earliest stages of PD, although there are inconsistencies in study findings due to the complexity of the executive function (EF) construct and methodological limitations. Behavioral disorders of PD, e.g., apathy, distractibility, perseverative behavior, and impulse-control disorders, may be viewed as the other side of dysexecutive syndrome. Despite the interrelationship between the cognitive and behavioral domains, some reports reveal that the two syndromes may be dissociated, suggesting that both aspects must be clinically assessed. EFs are widely associated with the prefrontal areas, although dysexecutive syndrome may be observed in patients with damage to other brain regions. EFs drive numerous abilities essential to daily life, such as prospective remembering and language comprehension, which may be impaired in PD subjects. Considering the impact of dysexecutive syndrome on independence and quality of life, early detection of executive impairment is crucial in the management of PD.
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