Evidence map›Paper›PMID 23162521›Full record

ArticleFrontiers in psychology2012

Cognitive and neural aspects of information processing in major depressive disorder: an integrative perspective.

Lara C Foland-Ross, Ian H Gotlib

Abstract read
In one paragraph

Article in Frontiers in psychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Trial
  2. Subjective cognition and mood in persistent chemotherapy-related cognitive impairment.Journal of cancer survivorship : research and practice · 2022
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  16. Connectivity patterns evoked by fearful faces demonstrate reduced flexibility across a shared dimension of adolescent anxiety and depression.Clinical psychological science : a journal of the Association for Psychological Science · 2023
    Article
  17. Article
  18. Distinct Effects of Anxiety and Depression on Updating Emotional Information in Working Memory.International journal of environmental research and public health · 2022
    Article
  19. Article
  20. Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study.Journal of child psychology and psychiatry, and allied disciplines · 2022
    Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lara C Foland-RossDepartment of Psychology, Stanford University Stanford, CA, USA.
Ian H Gotlib

Funding

Risk for Depression:Identifying and Altering Psychobiological MechanismsR01MH074849 · NIMH · STANFORD UNIVERSITY · PI GOTLIB, IAN H · 2006 to 2015
$6.2M
Neural and Behavioral Aspects of Information-Processing Biases in DepressionR01MH059259 · NIMH · STANFORD UNIVERSITY · PI GOTLIB, IAN H · 1999 to 2011
$5.9M
An Integrative Examination of Brain Structure and Function in Major DepressionF32MH090617 · NIMH · STANFORD UNIVERSITY · PI FOLAND-ROSS, LARA C · 2010 to 2012
$146k
NIMH NIH HHS F32 MH090617NIMH NIH HHS R01 MH059259NIMH NIH HHS R01 MH074849
6 · The paper itself

Abstract

Researchers using experimental paradigms to examine cognitive processes have demonstrated that Major Depressive Disorder (MDD) is associated not with a general deficit in cognitive functioning, but instead with more specific anomalies in the processing of negatively valenced material. Indeed, cognitive theories of depression posit that negative biases in the processing of information play a critical role in influencing the onset, maintenance, and recurrence of depressive episodes. In this paper we review findings from behavioral studies documenting that MDD is associated with specific difficulties in attentional disengagement from negatively valenced material, with tendencies to interpret information in a negative manner, with deficits in cognitive control in the processing of negative material, and with enhanced memory for negative material. To gain a better understanding of the neurobiological basis of these abnormalities, we also examine findings from functional neuroimaging studies of depression and show that dysfunction in neural systems that subserve emotion processing, inhibition, and attention may underlie and contribute to the deficits in cognition that have been documented in depressed individuals. Finally, we briefly review evidence from studies of children who are at high familial risk for depression that indicates that abnormalities in cognition and neural function are observable before the onset of MDD and, consequently, may represent a risk factor for the development of this disorder. By integrating research from cognitive and neural investigations of depression, we can gain a more comprehensive understanding not only of how cognitive and biological factors interact to affect the onset, maintenance, and course of MDD, but also of how such research can aid in the development of targeted strategies for the prevention and treatment of this debilitating disorder.

Indexed as

amygdalaattention biascognitive controldepressioninterpretation biasMDDmemory biasneuroimaging

Identifiers

PMID23162521
PMCPMC3495336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.