ArticleJournal of Indian Society of Periodontology2012
Presence of Helicobacter pylori in subgingival plaque of periodontitis patients with and without dyspepsia, detected by polymerase chain reaction and culture.
Article in Journal of Indian Society of Periodontology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- The association between chronic periodontitis and oral Helicobacter pylori: A meta-analysis.PloS one · 2019Pooled it
- Can eradication rate of gastric Helicobacter pylori be improved by killing oral Helicobacter pylori?World journal of gastroenterology · 2013Trial
- Review
- Oral Helicobacter pylori: a scoping review and pilot study on the PCR-culture detection paradox.Clinical oral investigations · 2026Article
- Oral urease rapid test serve as an effective complement to the detection of Helicobacter pylori infection through urea breath test.BMC gastroenterology · 2025Article
- Association ofMicroorganisms · 2025Review
- Comparative Evaluation of Tongue and Periodontal Pocket Microbiome in Relation toAntibiotics (Basel, Switzerland) · 2025Article
- Oral manifestations associated with gastrointestinal diseases - A review.Bioinformation · 2025Article
- Effect of mouthwash containing poly l-Lysine and glycerol monolaurate on oralJournal of dental sciences · 2024Article
- Oral Microbiota, a Potential Determinant for the Treatment Efficacy of GastricPolish journal of microbiology · 2022Article
- An Anaerobic Environment Drives the Harboring ofBiology · 2022Article
- Article
- Clinical manifestations of gastrointestinal diseases in the oral cavity.The Saudi dental journal · 2021Review
- Presence of non-oral bacteria in the oral cavity.Archives of microbiology · 2021Review
- In Vitro Incorporation ofPathogens (Basel, Switzerland) · 2020Article
- Recurrence of Helicobacter pylori infection: incidence and influential factors.Chinese medical journal · 2019Article
- GastricPeerJ · 2019Article
- Influence of Helicobacter pylori culture supernatant on the ecological balance of a dual-species oral biofilm.Journal of applied oral science : revista FOB · 2018Article
- Are the view of Helicobacter pylori colonized in the oral cavity an illusion?Experimental & molecular medicine · 2017Review
- Prevalence ofBioMed research international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHelicobacter pylori is an important gastrointestinal pathogen that is strongly associated with gastritis as well as peptic ulcer disease. Antimicrobial therapy frequently fails to cure H. pylori infection, which suggests there may be sanctuary sites where the organism resides. This study was aimed to assess the role of oral cavity as a reservoir of H. pylori by evaluating the occurrence of the organism in subgingival plaque of dyspeptic patients by polymerase chain reaction as well as culture. MATERIALS AND
methodsThirty chronic periodontitis patients whose biopsy specimens were found to be H. pylori positive with rapid urease test and histopathologic examination were considered as cases and 20 chronic periodontitis patients who never had any symptoms of gastritis or peptic ulcer were taken as controls. Subgingival plaque samples were collected and sent to microbiological laboratory for detection of H. pylori by 16S rRNA based polymerase chain reaction as well as culture.
results60% of the samples were found to be positive with polymerase chain reaction in the case group when compared to 15% in the controls. Also, 30% of the cases were found to be positive with culture compared to none in controls.
conclusionA higher frequency of detection of H. pylori in those patients with positive antral biopsy report was seen. Also, polymerase chain reaction was found to be more sensitive than culture for detection. Thus, we conclude that detection of H. pylori in dental plaque of dyspeptic patients cannot be neglected and might represent a risk factor for recolonization of stomach after systemic eradication therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.