Evidence map›Paper›PMID 23161830›Full record

ReviewDiagnostic cytopathology2014

Adenocarcinoma cells in effusion cytology as a diagnostic pitfall with potential impact on clinical management: a case report with brief review of immunomarkers.

Sinchita Roy Chowdhuri, Patricia Fetsch, Jennifer Squires, Elise Kohn, Armando C Filie

Abstract readCase ReportsReview
In one paragraph

Review in Diagnostic cytopathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sinchita Roy ChowdhuriCytopathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Patricia Fetsch
Jennifer Squires
Elise Kohn
Armando C Filie

Funding

Cytopathology CoreZICBC011052 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI FILIE, ARMANDO · 2009 to 2025
$30.8M
Cytopathology CoreZ01BC011052 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI FILIE, ARMANDO · 2008 to 2008
$1.5M
Intramural NIH HHS Z01 BC011052
6 · The paper itself

Abstract

Distinguishing metastatic carcinoma cells from reactive mesothelial cells in effusion samples is often challenging based on morphology alone. Metastatic carcinoma cells in fluid samples may mimic reactive mesothelial cells due to overlapping cytological features. We report a case of a pleural effusion in a 51-year-old female patient with a medical history significant for bilateral ovarian tumors and peritoneal implants diagnosed as serous tumor of borderline malignant potential. The effusion was composed almost entirely of adenocarcinoma cells that morphologically mimicked reactive mesothelial cells. The diagnosis of metastatic adenocarcinoma was made after a wide immunostaining panel of antibodies. Recognizing metastatic adenocarcinoma cells in effusion samples can be challenging and an accurate diagnosis may have significant impact on clinical management as demonstrated by this case.

Indexed as

AdenocarcinomaBiomarkers, TumorCytodiagnosisDiagnosis, DifferentialEpitheliumFemaleHumansOvarian NeoplasmsPleural Effusion, MalignantBiomarkers, Tumoradenocarcinoma cellscytologyeffusionimmunostainingreactive mesothelial cells

Identifiers

PMID23161830
PMCPMC7682751

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.