Evidence map›Paper›PMID 23161817›Full record

ReviewBiotechnology journal2013

Microfluidic tools for developmental studies of small model organisms--nematodes, fruit flies, and zebrafish.

Hyundoo Hwang, Hang Lu

Abstract readReview
In one paragraph

Review in Biotechnology journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Automated Platforms inMicromachines · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Microfluidic-AssistedCyborg and bionic systems (Washington, D.C.) · 2023
    Article
  7. Microfluidic systems for modeling human development.Development (Cambridge, England) · 2022
    Article
  8. UsingFrontiers in pharmacology · 2022
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hyundoo HwangSchool of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Hang Lu

Funding

Quantitative microscopy-based rapid phenotyping and screeningR01GM088333 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI LU, HANG · 2011 to 2018
$2.3M
Sources, transmission and effects of transcriptional noise in C. elegans agingR01AG035317 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI LU, HANG · 2009 to 2011
$837k
HIGH-THROUGHPUT HIGH-CONTENT PLATFORM FOR IMAGE-BASED SCREENSR21EB012803 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI LU, HANG · 2010 to 2011
$399k
Dissecting neural circuits by microfluidic-enabled rapid microscopy & ablationR21NS058465 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI LU, HANG · 2007 to 2008
$351k
NIA NIH HHS R01 AG035317NIA NIH HHS R01AG035317NIBIB NIH HHS R21 EB012803NIBIB NIH HHS R21EB012803NIGMS NIH HHS R01 GM088333NIGMS NIH HHS R01GM088333NINDS NIH HHS R21 NS058465
6 · The paper itself

Abstract

Studying the genetics of development with small model organisms such as the zebrafish (Danio Rerio), the fruit fly (Drosophila melanogaster), and the soil-dwelling nematode (Caenorhabditis elegans), provide unique opportunities for understanding related processes and diseases in humans. These model organisms also have potential for use in drug discovery and toxicity-screening applications. There have been sweeping developments in microfabrication and microfluidic technologies for manipulating and imaging small objects, including small model organisms, which allow high-throughput quantitative biological studies. Here, we review recent progress in microfluidic tools able to manipulate small organisms and project future directions and applications of these techniques and technologies.

Indexed as

Models, AnimalAnimalsCaenorhabditis elegansDrosophila melanogasterDrug DiscoveryEmbryonic DevelopmentMicrofluidicsZebrafish

Identifiers

PMID23161817
PMCPMC3918482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.