ArticleThe Veterinary record2013
Challenges and proposed solutions for more accurate serological diagnosis of equine infectious anaemia.
Article in The Veterinary record, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 55 citations in OpenAlex.
- Evaluation of synthetic peptides derived from glycoproteins gp45 and gp90 as candidates for the immunodiagnosis of equine infectious anemia.Veterinary research communications · 2026Article
- Comparative Evaluation of a Multistrain Indirect ELISA Targeting Anti- p26 and gp45 Antibodies for EIAV Detection.Pathogens (Basel, Switzerland) · 2025Article
- Serodiagnosis of equine infectious anemia by indirect ELISA based on a novel synthetic peptide derived from gp45 glycoprotein.Veterinary research communications · 2025Article
- Development and evaluation of a test strip for the rapid detection of antibody against equine infectious anemia virus.Applied microbiology and biotechnology · 2024Article
- Equine Infectious Anaemia: The Active Surveillance of an Entire Equid Population Reduces the Occurrence of the Infection.Transboundary and emerging diseases · 2024Article
- Development and evaluation of a blocking ELISA for serological diagnosis of equine infectious anemia.Applied microbiology and biotechnology · 2023Article
- Viral Diseases that Affect Donkeys and Mules.Animals : an open access journal from MDPI · 2020Review
- Prospects in Innate Immune Responses as Potential Control Strategies against Non-Primate Lentiviruses.Viruses · 2018Review
- A retrospective study of owner-requested testing as surveillance for equine infectious anemia in Canada (2009-2012).The Canadian veterinary journal = La revue veterinaire canadienne · 2017Article
- Evaluation of six serological ELISA kits available in Italy as screening tests for equine infectious anaemia surveillance.BMC veterinary research · 2017Article
- Freedom from equine infectious anaemia virus infection in Spanish Purebred horses.Veterinary record open · 2015Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serological diagnosis of equine infectious anaemia virus (EIAV) infections has depended mainly on the agar gel immunodiffusion test (AGIDT). This study documents the presence of EIAV genetic sequences in a number of persistently infected horses and mules whose serums were interpreted as negative/equivocal on AGIDT, but positive on more than one ELISA test and in immunoblot tests. Strategies designed to take advantage of the combined strengths of the ELISA and AGIDT are shown effective in a national surveillance program for EIA in Italy where 17 per cent (25/149) of the equids considered to be infected with EIAV on combined/comparative serological data had reactions in the AGIDT that were interpreted as negative or equivocal. These data document the benefits of using a three-tiered laboratory system for the diagnosis of EIA. Although the ELISA-first strategy introduces some confusing results, the discovery of up to 20 per cent more cases of EIA makes it compelling. In our opinion, it is better and more defensible to find two samples in 1000 with resolvable but falsely positive ELISA tests for EIA than to release two to three horses in 10,000 with falsely negative test results for EIA (the rates seen in the Italian surveillance presented here).
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