ArticleMacromolecular bioscience2013
Laminar silk scaffolds for aligned tissue fabrication.
Article in Macromolecular bioscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- A modular silk-collagen scaffold to model dorsoventral spinal cord organization using human pluripotent stem cells.Journal of materials chemistry. B · 2026Article
- Development of Biomimetic Edible Scaffolds for Cultured Meat Based on the Traditional Freeze-Drying Method forGels (Basel, Switzerland) · 2025Article
- Developing Porous Fibrin Scaffolds with Tunable Anisotropic Features to Direct Myoblast Orientation.Tissue engineering. Part C, Methods · 2024Article
- Scaffolding Biomaterials for 3D Cultivated Meat: Prospects and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Estimating Kinetic Rate Parameters for Enzymatic Degradation of Lyophilized Silk Fibroin Sponges.Frontiers in bioengineering and biotechnology · 2021Article
- Biomimetic angle-ply multi-lamellar scaffold for annulus fibrosus tissue engineering.Journal of materials science. Materials in medicine · 2020Article
- Bi-layered Tubular Microfiber Scaffolds as Functional Templates for Engineering Human Intestinal Smooth Muscle Tissue.Advanced functional materials · 2020Article
- Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Bombyx mori Silk Fibroin Scaffolds with Antheraea pernyi Silk Fibroin Micro/Nano Fibers for Promoting EA. hy926 Cell Proliferation.Materials (Basel, Switzerland) · 2017Article
- Shape Memory Silk Protein Sponges for Minimally Invasive Tissue Regeneration.Advanced healthcare materials · 2017Article
- Fabrication of anatomically-shaped cartilage constructs using decellularized cartilage-derived matrix scaffolds.Biomaterials · 2016Article
- The effect of sterilization on silk fibroin biomaterial properties.Macromolecular bioscience · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
3D-biomaterial scaffolds with aligned architecture are of vital importance in tissue regeneration. A generic method is demonstrated to produce aligned biomaterial scaffolds using the physics of directional ice freezing. Homogeneously aligned 3D silk scaffolds with high porosity and alignment are prepared. The method can be adapted to a wide range of polymers and is devoid of any chemical reactions, thus avoiding potential complications associated with by-products. Mechanical properties and cellular responses with chondrocytes and bone-marrow-derived hMSCs are studied, assessing survival, proliferation, and differentiation. In vivo tests suggest biocompatibility of the matrices for future tissue engineering applications, specifically in areas where high cellular alignment is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.