Evidence map›Paper›PMID 23161329›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2013

Functional status, life-space mobility, and quality of life: a longitudinal mediation analysis.

John P Bentley, Cynthia J Brown, Gerald McGwin, Patricia Sawyer, Richard M Allman, David L Roth

Registry-linked trialAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04934956 (Locomotor Adaptability for Community Mobility of Older Adults), which is not on this map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04934956 nacompletednot on this mapstarted 2021, after this paper: background citation

Locomotor Adaptability for Community Mobility of Older Adults: The Role of Gait Automaticity

TypeinterventionalSponsorUniversity of PittsburghRan2021 to 2025Enrolled44ConditionsCommunity Mobility of Older Adults, Locomotor Adaptability, Gait AutomaticityArmsSplit-belt walking, Multiple transitions between split-belt and tied-belt walking
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Association of Mobility Determinants and Life Space Among Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Trial
  3. Are Mobile Persons With Parkinson Disease Necessarily More Active?Journal of neurologic physical therapy : JNPT · 2021
    Trial
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  11. Observational
  12. Life-Space Mobility: Normative Values From a National Cohort of U.S. Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  13. Article
  14. Bidirectional Association Between Multimorbidity and Frailty and the Role of Depression in Older Europeans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  15. Article
  16. The Longitudinal Association Between Frailty, Cognition, and Quality of Life in Older Europeans.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John P BentleySchool of Pharmacy, University of Mississippi, Faser Hall 235, University, MS 38677, USA. phjpb@olemiss.edu
Cynthia J Brown
Gerald McGwin
Patricia Sawyer
Richard M Allman
David L Roth

Funding

UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUAY-WOODFORD, LISA MARIE · 2008 to 2011
$22.3M
MOBILITY AMONG OLDER AFRICAN AMERICANS AND WHITESR01AG015062 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BROWN, CYNTHIA J. · 1998 to 2014
$6.7M
NIA NIH HHS R01 AG015062
6 · The paper itself

Abstract

purposeUsing the Wilson-Cleary model of patient outcomes as a conceptual framework, the impact of functional status on health-related quality of life (HRQoL) among older adults was examined, including tests of the mediation provided by life-space mobility.

methodsParticipants were enrollees in a population-based, longitudinal study of mobility among community-dwelling older adults. Data from four waves of the study equally spaced approximately 18 months apart (baseline, 18, 36, and 54 months) were used for participants who survived at least 1 year beyond the 54-month assessment (n = 677). Autoregressive mediation models using longitudinal data and cross-sectional mediation models using baseline data were evaluated and compared using structural equation modeling.

resultsThe longitudinal autoregressive models supported the mediating role of life-space mobility and suggested that this effect is larger for the mental component summary score than the physical component summary score of the SF-12. Evidence for a reciprocal relationship over time between functional status, measured by ADL difficulty, and life-space mobility was suggested by modification indices; these model elaborations did not alter the substantive meaning of the mediation effects. Mediated effect estimates from longitudinal autoregressive models were generally larger than those from cross-sectional models, suggesting that mediating relationships would have been missed or were potentially underestimated in cross-sectional models.

conclusionsThese results support a mediating role for life-space mobility in the relationship between functional status and HRQoL. Functional status limitations might cause diminished HRQoL in part by limiting mobility. Mobility limitations may precede functional status limitations in addition to being a consequence thereof.

Indexed as

Activities of Daily LivingMobility LimitationAdultAgedAged, 80 and overFemaleGeriatric AssessmentHumansLongitudinal StudiesMaleModels, StatisticalQuality of LifeResidence CharacteristicsSickness Impact ProfileSurveys and Questionnaires

Identifiers

PMID23161329
PMCPMC3618999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.