ArticleJournal of materials science. Materials in medicine2013
Fluoride and calcium-phosphate coated sponges of the magnesium alloy AX30 as bone grafts: a comparative study in rabbits.
Article in Journal of materials science. Materials in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Overview of porous magnesium-based scaffolds: development, properties and biomedical applications.Materials futures · 2025Review
- The biological properties of 3D-printed degradable magnesium alloy WE43 porous scaffolds via the oxidative heat strategy.International journal of bioprinting · 2023Article
- Biofunctional magnesium coated Ti6Al4V scaffold enhances osteogenesis and angiogenesisBioactive materials · 2020Article
- Bioabsorbable high-purity magnesium interbody cage: degradation, interbody fusion, and biocompatibility from a goat cervical spine model.Annals of translational medicine · 2020Article
- A novel open-porous magnesium scaffold with controllable microstructures and properties for bone regeneration.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Biocompatibility and degradation of magnesium sponges (alloy AX30) with a fluoride (MgF(2) sponge, n = 24, porosity 63 ± 6 %, pore size 394 ± 26 μm) and with a fluoride and additional calcium-phosphate coating (CaP sponge, n = 24, porosity 6 ± 4 %, pore size 109 ± 37 μm) were evaluated over 6, 12 and 24 weeks in rabbit femurs. Empty drill holes (n = 12) served as controls. Clinical and radiological examinations, in vivo and ex vivo μ-computed tomographies and histological examinations were performed. Clinically both sponge types were tolerated well. Radiographs and XtremeCT evaluations showed bone changes comparable to controls and mild gas formation. The μCT80 depicted a higher and more inhomogeneous degradation of the CaP sponges. Histomorphometrically, the MgF(2) sponges resulted in the highest bone and osteoid fractions and were integrated superiorly into the bone. Histologically, the CaP sponges showed more inflammation and lower vascularization. MgF(2) sponges turned out to be better biocompatible and promising, biodegradable bone replacements.
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Registered trials
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