ArticleParasitology research2013
Comparative study of nitric oxide (NO) production during human hydatidosis: relationship with cystic fluid fertility.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Calprotectin Expression in Adventitial Layer of Cattle and SheepInternational journal of molecular sciences · 2025Article
- Evaluation of the Local Immune Response to Hydatid Cysts in Sheep Liver.Veterinary sciences · 2023Article
- Apoptosis as a Potential Target to Arrest and Survival of Hydatid Cyst.Advanced biomedical research · 2023Article
- Multiple haplotypes of Echinococcus granulosus sensu stricto in single naturally infected intermediate hosts.Parasitology research · 2020Article
- New insights of the local immune response against both fertile and infertile hydatid cysts.PloS one · 2019Article
- Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region.Mediators of inflammation · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human hydatidosis is characterized by a prolonged coexistence of Echinococcus granulosus and its host without effective rejection of the parasite. This parasitic infection constitutes a major health problem in Algeria. In this study, we investigated in vivo production of nitrite (NO(2)(-) + NO(3)(-)) in sera of Algerian patients carrying different cyst locations. Nitrite (NO(2)(-) + NO(3)(-)) levels were evaluated by the Griess method. Our results indicated that the levels of nitrite were significantly higher in the sera of hydatic patients than those of healthy controls supporting the involvement of nitric oxide (NO) in antihydatic action. The levels of nitrite in sera of the patients with hepatic hydatidosis were significantly higher than those with pulmonary infection. The lower serum (NO(2)(-) + NO(3)(-)) levels were observed in the relapsing cases. In addition, (NO(2)(-) + NO(3)(-)) levels of fertile hydatic fluids were significantly higher compared to infertile fluids. Our results suggest that the presence of NO products in hydatic fluids seems to be related to the location and the fertility of hydatic cysts. The assessment of protein concentration in hydatic fluids showed that the concentration of proteins was not exclusively dependent on the fertility but on the cyst locations. The assessment of (NO(2)(-) + NO(3)(-)) production in hydatic patients may be a useful tool to evaluate effector mechanisms of NO and clinical manifestations.
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