ArticleIntensive care medicine2013
Intubation-related tracheal ischemic lesions: incidence, risk factors, and outcome.
Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 70 citations in OpenAlex.
- Bench testing a contact sensing tracheal tube for monitoring the cuff-trachea interface.BMC biomedical engineering · 2026Article
- The investigation of initial endotracheal tube cuff pressures in the operating room: a multi-center cross-sectional study in China.Scientific reports · 2026Article
- In-vitro endo tracheal tube cuff pressure decreases following transport via helicopter: implications for medical evacuation of military working dogs.BMC veterinary research · 2025Article
- Prevalence and degree of orotracheal intubation-related tracheal lesions in horses.Equine veterinary journal · 2025Article
- Article
- Triglyceride glucose index and mortality in tracheally intubated patients: a MIMIC-IV retrospective cohort study.PloS one · 2025Article
- Changes of endotracheal tube cuff pressure and its indicators in laparoscopic resection of colorectal neoplasms: an observational prospective clinical trial.BMC anesthesiology · 2024Observational
- Observational
- Multidisciplinary management of laryngeal pathology identified in patients with COVID-19 following trans-laryngeal intubation and tracheostomy.Journal of the Intensive Care Society · 2022Article
- Complications of invasive mechanical ventilation in critically Ill Covid-19 patients - A narrative review.Annals of medicine and surgery (2012) · 2022Review
- Molecular Mechanisms and Physiological Changes behind Benign Tracheal and Subglottic Stenosis in Adults.International journal of molecular sciences · 2022Review
- Experimental Assessment of Cuff Pressures on the Walls of a Trachea-Like Model Using Force Sensing Resistors: Insights for Patient Management in Intensive Care Unit Settings.Sensors (Basel, Switzerland) · 2022Article
- The Relationship between Cuff Pressure and Air Injection Volume of Endotracheal Tube: A Study with Sheep Trachea Ex Vivo.Applied bionics and biomechanics · 2022Article
- A mobile terminal application program was used for endotracheal tube cuff pressure measurement.Journal of clinical monitoring and computing · 2021Article
- Post-intubation subglottic stenosis: aetiology at the cellular and molecular level.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- [Airway management for lung separation in thoracic surgery : An update].Der Anaesthesist · 2018Review
- Incidence of airway complications in patients using endotracheal tubes with continuous aspiration of subglottic secretions.Annals of intensive care · 2017Article
- Altitude-Related Change in Endotracheal Tube Cuff Pressures in Helicopter EMS.The western journal of emergency medicine · 2017Article
- A canine model of tracheal stenosis induced by cuffed endotracheal intubation.Scientific reports · 2017Article
- Efficiency of an electronic device in controlling tracheal cuff pressure in critically ill patients: a randomized controlled crossover study.Annals of intensive care · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation.
methodsPlanned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ulcer or tracheal rupture, fiberoptic tracheoscopy was repeated 2 weeks after the last extubation. Tracheal ischemic lesions were predefined based on a quantitative score.
resultsNinety-six adult patients were included in this study. Eighty (83 %) patients had at least one tracheal ischemic lesion. Thirty-seven (38 %) patients had a tracheal ischemia score > median score (5; IQ 1, 7). The most common tracheal ischemic lesion was ischemia (68 %), followed by hyperemia (54 %), ulcer (10 %), and tracheal rupture (1 %). Univariate analysis identified duration of neuromuscular-blocking agent use, overinflation of tracheal cuff (>30 cmH2O), percentage of P cuff determination >30 cmH2O, duration of assist-control ventilation, and plateau pressure as risk factors for having a tracheal ischemia score >5. Duration of assist-control mechanical ventilation was the only factor independently associated with tracheal ischemia score >5 [OR (95 % CI) 1.10 per hour (1.02-1.20)]. A fiberoptic tracheoscopy was performed 2 weeks after extubation in 22 patients. This examination was normal in all patients, except the one with tracheal rupture who had marked improvement.
conclusionTracheal ischemic lesions are common in intubated, critically ill patients. Duration of assist-control mechanical ventilation through a tracheal tube is the only independent risk factor. These lesions healed in the majority of patients 2 weeks after extubation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.