Evidence map›Paper›PMID 23160723›Full record

ArticleDiabetes care2013

Association of electrocardiographically determined left ventricular mass with incident diabetes, 1985-1986 to 2010-2011: Coronary Artery Risk Development in Young Adults (CARDIA) study.

Mercedes R Carnethon, Hongyan Ning, Elsayed Z Soliman, Cora E Lewis, Pamela J Schreiner, Stephen Sidney, Donald M Lloyd-Jones

Open access · hybridAbstract read
In one paragraph

Article in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Abnormal electrocardiographic QRS transition zone and risk of mortality in individuals free of cardiovascular disease.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mercedes R CarnethonDepartment of Preventive Medicine, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA. carnethon@northwestern.edu
Hongyan Ning
Elsayed Z Soliman
Cora E Lewis
Pamela J Schreiner
Stephen Sidney
Donald M Lloyd-Jones
Northwestern University · USKaiser Permanente · USUniversity of Alabama at Birmingham · USUniversity of Minnesota · USWake Forest University · US

Funding

VASCULAR CALCIUM--AN EPIDEMIOLOGIC STUDYR01HL048050 · NHLBI · UNIVERSITY OF IOWA · PI MAHONEY, LARRY T · 1992 to 2004
$3.0M
REGULATION OF LUNG SURFACTANT PROTEIN B GENE EXPRESSIONR01HL048048 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI BOGGARAM, VIJAYAKUMAR · 1998 to 2006
$1.3M
Epidemiology and Mechanisms of ECG Abnormalities: Young Adulthood to Middle AgeR01HL086792 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2007 to 2009
$1.2M
CORONARY ARTERY DISEASE RISK DEVELOPMENT IN YOUNG ADULTS-N01HC95095-268095095N01HC095095 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, DALE · 1989 to 2006
$376k
CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048047 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 1985 to 2000
$171k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048049 · HC · NORTHWESTERN UNIVERSITY · PI LIU, KIANG JOHN · 1985 to 2000
$71k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048048 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHREINER, PAMELA J · 1985 to 2000
$53k
RETROVIRAL TRANSDUCTION OF CLASS I MHC GENER01HL048049 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SACHS, DAVID H · 1993 to 1997
–
REGULATION OF LUNG SURFACTANT PROTEIN B GENE EXPRESSIONR29HL048048 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI BOGGARAM, VIJAYAKUMAR · 1993 to 1997
–
NHLBI NIH HHS N01 HC048047NHLBI NIH HHS N01 HC048048NHLBI NIH HHS N01 HC048049NHLBI NIH HHS N01 HC048050NHLBI NIH HHS N01 HC095095NHLBI NIH HHS N01-HC-48047NHLBI NIH HHS N01-HC-48048NHLBI NIH HHS N01-HC-48049NHLBI NIH HHS N01-HC-48050NHLBI NIH HHS N01-HC-95095NHLBI NIH HHS R01 HL086792NHLBI NIH HHS R01-HL-086792
6 · The paper itself

Abstract

objectiveElectrocardiographic indices reflecting left ventricular hypertrophy are associated with incident diabetes in clinical populations at risk for coronary heart disease. We tested whether electrocardiographically determined left ventricular mass was positively associated with incident diabetes in a population sample. RESEARCH DESIGN AND

methodsCoronary Artery Risk Development in Young Adults (CARDIA) study participants (n = 4,739) were followed from 1985-1986 to 2010-2011 for incident diabetes. Validated sex- and race-specific formulas were applied to standard electrocardiograms to determine left ventricular mass.

resultsOver 25 years, 444 participants developed diabetes (9.4%). After adjustment for demographic, behavioral, and clinical covariates, participants in the highest quartile of left ventricular mass index (LVMI) were twice as likely to develop diabetes than participants in the lower three quartiles (hazard ratio 2.61 [95% CI 2.16-3.17]). Neither Cornell voltage nor Cornell voltage product was associated with incident diabetes in fully adjusted models.

conclusionsElectrocardiographically determined LVMI may be a useful noninvasive marker for identifying adults at risk for diabetes.

Indexed as

AdultDiabetes MellitusElectrocardiographyFemaleHumansHypertrophy, Left VentricularMaleVentricular Dysfunction, LeftYoung Adult

Identifiers

PMID23160723
PMCPMC3579342
OpenAlexW2079489493

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.