Evidence map›Paper›PMID 23160415›Full record

ArticleDatabase : the journal of biological databases and curation2012

Prioritizing PubMed articles for the Comparative Toxicogenomic Database utilizing semantic information.

Sun Kim, Won Kim, Chih-Hsuan Wei, Zhiyong Lu, W John Wilbur

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Using deep learning to identify translational research in genomic medicine beyond bench to bedside.Database : the journal of biological databases and curation · 2019
    Article
  2. Article
  3. Assisting document triage for human kinome curation via machine learning.Database : the journal of biological databases and curation · 2018
    Article
  4. Article
  5. Animal-Free Chemical Safety Assessment.Frontiers in pharmacology · 2016
    Review
  6. Article
  7. Scaling drug indication curation through crowdsourcing.Database : the journal of biological databases and curation · 2015
    Article
  8. Article
  9. CoIN: a network analysis for document triage.Database : the journal of biological databases and curation · 2013
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sun KimNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Won Kim
Chih-Hsuan Wei
Zhiyong Lu
W John Wilbur

Funding

National Biomedical Information ServicesZIHLM200888 · NLM · NATIONAL LIBRARY OF MEDICINE · PI PALTOO, DINA · 2009 to 2025
$5200.7M
Named Entity Recognition and Relationship Extraction in BiomedicineZIALM091813 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2013 to 2022
$13.4M
Natural Language Processing Techniques To Enhance Information Access.ZIALM000090 · NLM · NATIONAL LIBRARY OF MEDICINE · PI WILBUR, WILLY · 2009 to 2015
$3.4M
Free Text Gene Name RecognitionZIALM000093 · NLM · NATIONAL LIBRARY OF MEDICINE · PI WILBUR, WILLY · 2009 to 2015
$1.6M
Intramural NIH HHS
6 · The paper itself

Abstract

The Comparative Toxicogenomics Database (CTD) contains manually curated literature that describes chemical-gene interactions, chemical-disease relationships and gene-disease relationships. Finding articles containing this information is the first and an important step to assist manual curation efficiency. However, the complex nature of named entities and their relationships make it challenging to choose relevant articles. In this article, we introduce a machine learning framework for prioritizing CTD-relevant articles based on our prior system for the protein-protein interaction article classification task in BioCreative III. To address new challenges in the CTD task, we explore a new entity identification method for genes, chemicals and diseases. In addition, latent topics are analyzed and used as a feature type to overcome the small size of the training set. Applied to the BioCreative 2012 Triage dataset, our method achieved 0.8030 mean average precision (MAP) in the official runs, resulting in the top MAP system among participants. Integrated with PubTator, a Web interface for annotating biomedical literature, the proposed system also received a positive review from the CTD curation team.

Indexed as

Databases, FactualPeriodicals as TopicPubMedSemanticsToxicogeneticsModels, Theoretical

Identifiers

PMID23160415
PMCPMC3500521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.