Evidence map›Paper›PMID 23160280›Full record

ArticleNature methods2013

Streaming fragment assignment for real-time analysis of sequencing experiments.

Adam Roberts, Lior Pachter

Abstract read
In one paragraph

Article in Nature methods, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 570 papers.

0numbers the graph read from it
0cells of the map it votes in
570citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

570 citing papers in PubMed.

  1. Trial
  2. Article
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  6. Article
  7. Salamander-Ecology and evolution · 2026
    Article
  8. Article
  9. Article
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  15. Article
  16. Article
  17. Article
  18. Review
  19. Photoperiod-driven gene regulation in the brain ofFrontiers in endocrinology · 2026
    Article
  20. Article

510 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam RobertsDepartment of Computer Science, University of California, Berkeley, Berkeley, California, USA.
Lior Pachter

Funding

Methods for the analysis of RNA-Seq and related sequence census based experimentsR01HG006129 · NHGRI · UNIVERSITY OF CALIFORNIA BERKELEY · PI PACHTER, LIOR S · 2011 to 2013
$1.1M
NHGRI NIH HHS R01 HG006129NHGRI NIH HHS R01HG006129
6 · The paper itself

Abstract

We present eXpress, a software package for efficient probabilistic assignment of ambiguously mapping sequenced fragments. eXpress uses a streaming algorithm with linear run time and constant memory use. It can determine abundances of sequenced molecules in real time and can be applied to ChIP-seq, metagenomics and other large-scale sequencing data. We demonstrate its use on RNA-seq data and show that eXpress achieves greater efficiency than other quantification methods.

Indexed as

AlgorithmsChromatin ImmunoprecipitationComputational BiologyGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansOligonucleotide Array Sequence AnalysisRNASequence Analysis, DNASequence Analysis, RNASoftwareRNA

Identifiers

PMID23160280
PMCPMC3880119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.