Evidence map›Paper›PMID 23160206›Full record

ArticleNature immunology2012

HOIL and water: the two faces of HOIL-1 deficiency.

Michael J Ombrello, Daniel L Kastner, Joshua D Milner

Abstract readNewsComment
PubMed Publisher
In one paragraph

Article in Nature immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Lessons learned from the study of human inborn errors of innate immunity.The Journal of allergy and clinical immunology · 2019
    Review
  2. Article
  3. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  4. Review
  5. Review
  6. When less is more: primary immunodeficiency with an autoinflammatory kick.Current opinion in allergy and clinical immunology · 2014
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Michael J Ombrello
Daniel L Kastner
Joshua D Milner

Funding

Genetics, Pathophysiology, and Treatment of Recessive Autoinflammatory DiseasesZIAHG200372 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI KASTNER, DANIEL · 2011 to 2025
$27.2M
Genetics, Pathophysiology, and Treatment of Dominant Autoinflammatory DiseasesZIAHG200373 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI KASTNER, DANIEL · 2011 to 2024
$21.0M
Genetic and Pathophysiologic Study of Atopic DiseaseZIAAI001183 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MILNER, JOSHUA · 2013 to 2019
$8.7M
Intramural NIH HHS Z99 AR999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Glycogen Storage Disease Type IVHereditary Autoinflammatory DiseasesHumansImmunologic Deficiency SyndromesNF-kappa BTranscription FactorsUbiquitin-Protein LigasesNF-kappa BRBCK1 protein, humanTranscription FactorsUbiquitin-Protein Ligases

Identifiers

PMID23160206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.