ArticleJournal of theoretical biology2013
Information-theoretic uncertainty of SCFG-modeled folding space of the non-coding RNA.
Article in Journal of theoretical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Secondary structural entropy in RNA switch (Riboswitch) identification.BMC bioinformatics · 2015Article
- RNA Thermodynamic Structural Entropy.PloS one · 2015Article
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4 authors.
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Abstract
unlabelledRNA secondary structure ensembles define probability distributions for alternative equilibrium secondary structures of an RNA sequence. Shannon's entropy is a measure for the amount of diversity present in any ensemble. In this work, Shannon's entropy of the SCFG ensemble on an RNA sequence is derived and implemented in polynomial time for both structurally ambiguous and unambiguous grammars. Micro RNA sequences generally have low folding entropy, as previously discovered. Surprisingly, signs of significantly high folding entropy were observed in certain ncRNA families. More effective models coupled with targeted randomization tests can lead to a better insight into folding features of these families. AVAILABILITY: URL http://www.plantbio.uga.edu/~russell/index.php?s=1&n=5&r=0.
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