Evidence map›Paper›PMID 23159919›Full record

ArticleBio Systems2013

Self-organization and entropy reduction in a living cell.

Paul C W Davies, Elisabeth Rieper, Jack A Tuszynski

Abstract read
In one paragraph

Article in Bio Systems, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Form and function in biological filaments: a physicist's review.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Review
  5. Article
  6. Directionality theory and the origin of life.Royal Society open science · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Entropy Perspectives of Molecular and Evolutionary Biology.International journal of molecular sciences · 2022
    Review
  12. Arrow of Time, Entropy, and Protein Folding: Holistic View on Biochirality.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Article
  15. Review
  16. Emergent Bioanalogous Properties of Blockchain-based Distributed Systems.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2021
    Article
  17. Review
  18. Dynamics of living cells in a cytomorphological state space.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paul C W DaviesBeyond Center for Fundamental Concepts in Science, Arizona State University, Tempe, AZ 85287-1504, USA.
Elisabeth Rieper
Jack A Tuszynski

Funding

Trans-NetworkU54CA143862 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MELDRUM, DEIRDRE R. · 2009 to 2013
$8.4M
NCI NIH HHS U54 CA143682NCI NIH HHS U54 CA143862
6 · The paper itself

Abstract

In this paper we discuss the entropy and information aspects of a living cell. Particular attention is paid to the information gain on assembling and maintaining a living state. Numerical estimates of the information and entropy reduction are given and discussed in the context of the cell's metabolic activity. We discuss a solution to an apparent paradox that there is less information content in DNA than in the proteins that are assembled based on the genetic code encrypted in DNA. When energy input required for protein synthesis is accounted for, the paradox is clearly resolved. Finally, differences between biological information and instruction are discussed.

Indexed as

EntropyInformation TheoryCellsDNAGenetic CodeModels, TheoreticalProbabilityProtein BiosynthesisProteinsThermodynamicsDNAProteins

Identifiers

PMID23159919
PMCPMC3712629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.