ReviewNeuropharmacology2013
New insights on neurobiological mechanisms underlying alcohol addiction.
Review in Neuropharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Substance Use and Non-Suicidal Self-Injury among Adolescents: A Meta-Analysis of Association Patterns and Moderating Factors.Journal of youth and adolescence · 2026Pooled it
- Pharmacological Treatment of ADHD in Addicted Patients: What Does the Literature Tell Us?Harvard review of psychiatryPooled it
- Chronic Alcohol Exposure Alters Expression of GluN3A-NMDA Receptors in Adult VTA DA Neurons.bioRxiv : the preprint server for biology · 2026Article
- Activation of anoctamin-1 calcium-activated chloride channels reduces voluntary alcohol consumption in rats.Neuropharmacology · 2025Article
- Synaptic Effects Induced by Alcohol.Current topics in behavioral neurosciences · 2025Review
- Targeting corticotropin-releasing hormone receptor type 1 (Crhr1) neurons: validating the specificity of a novel transgenic Crhr1-FlpO mouse.Brain structure & function · 2024Article
- Variants of the P3 event-related potential operate as indicators of distinct mechanisms contributing to problematic alcohol use.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Inhibition of the Sodium-Calcium Exchanger Reverse Mode Activity Reduces Alcohol Consumption in Rats.International journal of molecular sciences · 2024Article
- Bridging the Gap: A Holistic View of Personality Factors in Individuals With and Without Alcohol Use.Cureus · 2024Review
- Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder.Alcohol, clinical & experimental research · 2024Article
- Stress-induced red nucleus attenuation induces anxiety-like behavior and lymph node CCL5 secretion.Nature communications · 2023Article
- Chronic stress-induced synaptic changes to corticotropin-releasing factor-signaling in the bed nucleus of the stria terminalis.Frontiers in behavioral neuroscience · 2022Review
- Chronic intermittent ethanol during adolescence and adulthood alters dendritic spines in the primary motor and visual cortex in rats.Alcohol (Fayetteville, N.Y.) · 2021Article
- Influence of dopamine-related genes on craving, impulsivity, and aggressiveness in Korean males with alcohol use disorder.European archives of psychiatry and clinical neuroscience · 2021Article
- Neural network involving medial orbitofrontal cortex and dorsal periaqueductal gray regulation in human alcohol abuse.Science advances · 2021Article
- Probiotics-Based Treatment as an Integral Approach for Alcohol Use Disorder in Alcoholic Liver Disease.Frontiers in pharmacology · 2021Review
- [Binge drinking: the challenges of definition and its impact on health.]Revista espanola de salud publica · 2020Article
- Ethanol-Induced Changes in Brain of Transgenic Mice Overexpressing DYRK1A.Molecular neurobiology · 2020Article
- Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach.Molecular neurobiology · 2019Article
- A comparison of hippocampal microglial responses in aged and young rodents following dependent and non-dependent binge drinking.International review of neurobiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
Alcohol dependence/addiction is mediated by complex neural mechanisms that involve multiple brain circuits and neuroadaptive changes in a variety of neurotransmitter and neuropeptide systems. Although recent studies have provided substantial information on the neurobiological mechanisms that drive alcohol drinking behavior, significant challenges remain in understanding how alcohol-induced neuroadaptations occur and how different neurocircuits and pathways cross-talk. This review article highlights recent progress in understanding neural mechanisms of alcohol addiction from the perspectives of the development and maintenance of alcohol dependence. It provides insights on cross talks of different mechanisms and reviews the latest studies on metaplasticity, structural plasticity, interface of reward and stress pathways, and cross-talk of different neural signaling systems involved in binge-like drinking and alcohol dependence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.