Evidence map›Paper›PMID 23158582›Full record

ArticleFunctional neurology

Mortality and prognosis in patients with neurogenic orthostatic hypotension.

Simona Maule, Valeria Milazzo, Milena Maria Maule, Cristina Di Stefano, Alberto Milan, Franco Veglio

Abstract read
In one paragraph

Article in Functional neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

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  11. Strategies to improve the quality of life in patients with hereditary transthyretin amyloidosis (hATTR) and autonomic neuropathy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2019
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  20. Pure Autonomic Failure.Current neurology and neuroscience reports · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Simona MauleAutonomic Unit and Hypertension Center, Department of Medicine and Experimental Oncology, University of Turin and S. Giovanni Battista Hospital, Italy. simmaule@tin.it
Valeria Milazzo
Milena Maria Maule
Cristina Di Stefano
Alberto Milan
Franco Veglio
Azienda Ospedaliero Universitaria San Giovanni Battista · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of neurogenic orthostatic hypotension (NOH) has been poorly studied. The aim of this study was to evaluate retrospectively comorbidities and causes of death in patients with NOH. Clinical information and causes of death were obtained for 104 patients (45 with multiple system atrophy, 9 with pure autonomic failure, 43 with Parkinson's disease, and 7 with other types of autonomic neuropathy) referred to the Autonomic Unit from 1996 to 2009. Cardiovascular diseases (hypertension, cardiac comorbidities, atrial fibrillation and heart failure) were present in 53 (51%) NOH patients. At the end of follow-up, 44 patients were deceased. Type of NOH was the main factor associated with mortality. The main causes of death were infectious/respiratory (54%) and cardiac (16%). In NOH patients, cardiovascular diseases are frequent, although mortality is mainly due to infectious and respiratory causes. Detection of cardiovascular diseases may be useful in the choice of anti-hypotensive treatments.

Indexed as

AdultAgedAged, 80 and overAutonomic Nervous System DiseasesComorbidityFemaleHumansHypotension, OrthostaticMaleMiddle AgedMultiple System AtrophyParkinson DiseasePrognosisRetrospective Studies

Identifiers

PMID23158582
PMCPMC3812778
OpenAlexW14061662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.